日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

口服集落刺激因子 1 受体抑制剂 PLX3397 治疗复发性胶质母细胞瘤:Ivy 基金会早期临床试验联盟 II 期研究

Butowski, Nicholas; Colman, Howard; De Groot, John F; Omuro, Antonio M; Nayak, Lakshmi; Wen, Patrick Y; Cloughesy, Timothy F; Marimuthu, Adhirai; Haidar, Sam; Perry, Arie; Huse, Jason; Phillips, Joanna; West, Brian L; Nolop, Keith B; Hsu, Henry H; Ligon, Keith L; Molinaro, Annette M; Prados, Michael

Bial trial disaster

比尔审判灾难

Nolop, Keith

Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer

维莫非尼治疗BRAF突变转移性结直肠癌患者的II期试点研究

Kopetz, Scott; Desai, Jayesh; Chan, Emily; Hecht, Joel Randolph; O'Dwyer, Peter J; Maru, Dipen; Morris, Van; Janku, Filip; Dasari, Arvind; Chung, Woonbook; Issa, Jean-Pierre J; Gibbs, Peter; James, Brian; Powis, Garth; Nolop, Keith B; Bhattacharya, Suman; Saltz, Leonard

Long-term outcome in BRAF(V600E) melanoma patients treated with vemurafenib: Patterns of disease progression and clinical management of limited progression

接受维莫非尼治疗的BRAF(V600E)黑色素瘤患者的长期预后:疾病进展模式和有限进展的临床管理

Puzanov, Igor; Amaravadi, Ravi K; McArthur, Grant A; Flaherty, Keith T; Chapman, Paul B; Sosman, Jeffrey A; Ribas, Antoni; Shackleton, Mark; Hwu, Patrick; Chmielowski, Bartosz; Nolop, Keith B; Lin, Paul S; Kim, Kevin B

Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor

高特异性双重FMS和KIT激酶抑制剂的设计和药理学研究

Zhang, Chao; Ibrahim, Prabha N; Zhang, Jiazhong; Burton, Elizabeth A; Habets, Gaston; Zhang, Ying; Powell, Ben; West, Brian L; Matusow, Bernice; Tsang, Garson; Shellooe, Rafe; Carias, Heidi; Nguyen, Hoa; Marimuthu, Adhirai; Zhang, Kam Y J; Oh, Angela; Bremer, Ryan; Hurt, Clarence R; Artis, Dean R; Wu, Guoxian; Nespi, Marika; Spevak, Wayne; Lin, Paul; Nolop, Keith; Hirth, Peter; Tesch, Greg H; Bollag, Gideon

Clinical responses to vemurafenib in patients with metastatic papillary thyroid cancer harboring BRAF(V600E) mutation

维莫非尼治疗携带 BRAF(V600E) 突变的转移性乳头状甲状腺癌患者的临床疗效

Kim, Kevin B; Cabanillas, Maria E; Lazar, Alexander J; Williams, Michelle D; Sanders, Deborah L; Ilagan, Joseph L; Nolop, Keith; Lee, Richard J; Sherman, Steven I

Analysis of dermatologic events in vemurafenib-treated patients with melanoma

对接受维莫非尼治疗的黑色素瘤患者的皮肤病事件进行分析

Lacouture, Mario E; Duvic, Madeleine; Hauschild, Axel; Prieto, Victor G; Robert, Caroline; Schadendorf, Dirk; Kim, Caroline C; McCormack, Christopher J; Myskowski, Patricia L; Spleiss, Olivia; Trunzer, Kerstin; Su, Fei; Nelson, Betty; Nolop, Keith B; Grippo, Joseph F; Lee, Richard J; Klimek, Matthew J; Troy, James L; Joe, Andrew K

RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors

接受 BRAF 抑制剂治疗的患者皮肤鳞状细胞癌中的 RAS 突变

Su, Fei; Viros, Amaya; Milagre, Carla; Trunzer, Kerstin; Bollag, Gideon; Spleiss, Olivia; Reis-Filho, Jorge S; Kong, Xiangju; Koya, Richard C; Flaherty, Keith T; Chapman, Paul B; Kim, Min Jung; Hayward, Robert; Martin, Matthew; Yang, Hong; Wang, Qiongqing; Hilton, Holly; Hang, Julie S; Noe, Johannes; Lambros, Maryou; Geyer, Felipe; Dhomen, Nathalie; Niculescu-Duvaz, Ion; Zambon, Alfonso; Niculescu-Duvaz, Dan; Preece, Natasha; Robert, Lídia; Otte, Nicholas J; Mok, Stephen; Kee, Damien; Ma, Yan; Zhang, Chao; Habets, Gaston; Burton, Elizabeth A; Wong, Bernice; Nguyen, Hoa; Kockx, Mark; Andries, Luc; Lestini, Brian; Nolop, Keith B; Lee, Richard J; Joe, Andrew K; Troy, James L; Gonzalez, Rene; Hutson, Thomas E; Puzanov, Igor; Chmielowski, Bartosz; Springer, Caroline J; McArthur, Grant A; Sosman, Jeffrey A; Lo, Roger S; Ribas, Antoni; Marais, Richard

Marked, homogeneous, and early [18F]fluorodeoxyglucose-positron emission tomography responses to vemurafenib in BRAF-mutant advanced melanoma

在BRAF突变型晚期黑色素瘤中,维莫非尼治疗显示出显著、均质且早期的[18F]氟代脱氧葡萄糖正电子发射断层扫描反应

McArthur, Grant A; Puzanov, Igor; Amaravadi, Ravi; Ribas, Antoni; Chapman, Paul; Kim, Kevin B; Sosman, Jeffrey A; Lee, Richard J; Nolop, Keith; Flaherty, Keith T; Callahan, Jason; Hicks, Rodney J

Improved survival with vemurafenib in melanoma with BRAF V600E mutation

维莫非尼治疗BRAF V600E突变型黑色素瘤可提高生存率

Chapman, Paul B; Hauschild, Axel; Robert, Caroline; Haanen, John B; Ascierto, Paolo; Larkin, James; Dummer, Reinhard; Garbe, Claus; Testori, Alessandro; Maio, Michele; Hogg, David; Lorigan, Paul; Lebbe, Celeste; Jouary, Thomas; Schadendorf, Dirk; Ribas, Antoni; O'Day, Steven J; Sosman, Jeffrey A; Kirkwood, John M; Eggermont, Alexander M M; Dreno, Brigitte; Nolop, Keith; Li, Jiang; Nelson, Betty; Hou, Jeannie; Lee, Richard J; Flaherty, Keith T; McArthur, Grant A