A gated hydrophobic funnel within BAX binds bioactive lipids to potentiate pro-apoptotic function
BAX 内部的门控疏水漏斗可结合生物活性脂质,从而增强其促凋亡功能。
期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69836-9
Gelles, Jesse D; Chen, Yiyang; Luna-Vargas, Mark P A; Viacava Follis, Ariele; Al Noman, Md Abdullah; Kabir, Md; Bayiokos, Stella G; Mohammed, Jarvier N; Sebastian, Tara M; Pham, Ngoc Dung; Shi, Yi; Jin, Jian; Kriwacki, Richard W; Chipuk, Jerry Edward