日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Afamitresgene autoleucel for advanced synovial sarcoma and myxoid round cell liposarcoma (SPEARHEAD-1): an international, open-label, phase 2 trial

Afamitresgene autoleucel 用于晚期滑膜肉瘤和黏液样圆形细胞脂肪肉瘤(SPEARHEAD-1):一项国际性、开放标签的 II 期试验

D'Angelo, Sandra P; Araujo, Dejka M; Abdul Razak, Albiruni R; Agulnik, Mark; Attia, Steven; Blay, Jean-Yves; Carrasco Garcia, Irene; Charlson, John A; Choy, Edwin; Demetri, George D; Druta, Mihaela; Forcade, Edouard; Ganjoo, Kristen N; Glod, John; Keedy, Vicki L; Le Cesne, Axel; Liebner, David A; Moreno, Victor; Pollack, Seth M; Schuetze, Scott M; Schwartz, Gary K; Strauss, Sandra J; Tap, William D; Thistlethwaite, Fiona; Valverde Morales, Claudia Maria; Wagner, Michael J; Wilky, Breelyn A; McAlpine, Cheryl; Hudson, Laura; Navenot, Jean-Marc; Wang, Tianjiao; Bai, Jane; Rafail, Stavros; Wang, Ruoxi; Sun, Amy; Fernandes, Lilliam; Van Winkle, Erin; Elefant, Erica; Lunt, Colin; Norry, Elliot; Williams, Dennis; Biswas, Swethajit; Van Tine, Brian A

Autologous T cell therapy for MAGE-A4+ solid cancers in HLA-A*02+ patients: a phase 1 trial

自体T细胞疗法治疗HLA-A*02+患者MAGE-A4+实体瘤:一项I期试验

David S Hong #,Brian A Van Tine #,Swethajit Biswas,Cheryl McAlpine,Melissa L Johnson,Anthony J Olszanski,Jeffrey M Clarke,Dejka Araujo,George R Blumenschein Jr,Partow Kebriaei,Quan Lin,Alex J Tipping,Joseph P Sanderson,Ruoxi Wang,Trupti Trivedi,Thejo Annareddy,Jane Bai,Stavros Rafail,Amy Sun,Lilliam Fernandes,Jean-Marc Navenot,Frederic D Bushman,John K Everett,Derin Karadeniz,Robyn Broad,Martin Isabelle,Revashnee Naidoo,Natalie Bath,Gareth Betts,Zohar Wolchinsky,Dzmitry G Batrakou,Erin Van Winkle,Erica Elefant,Armin Ghobadi,Amanda Cashen,Anne Grand'Maison,Philip McCarthy,Paula M Fracasso,Elliot Norry,Dennis Williams,Mihaela Druta,David A Liebner,Kunle Odunsi,Marcus O Butler

Durable control of metastases in an HLA-A2+ patient with refractory melanoma after low-dose radiotherapy in combination with MAGE-A4 T cell therapy: a case report

低剂量放疗联合MAGE-A4 T细胞疗法治疗HLA-A2阳性难治性黑色素瘤患者后,转移灶得到持久控制:病例报告

He, Kewen; Hong, David S; Ke, Danxia; Kebriaei, Partow; Wang, Tianjiao; Danesi, Hassan; Bertolet, Genevieve; Leuschner, Carola; Puebla-Osorio, Nahum; Voss, Tiffany A; Lin, Quan; Norry, Elliot; Fracasso, Paula M; Welsh, James W

Phase I clinical trial evaluating the safety and efficacy of ADP-A2M10 SPEAR T cells in patients with MAGE-A10(+) advanced non-small cell lung cancer

一项评估 ADP-A2M10 SPEAR T 细胞治疗 MAGE-A10(+) 晚期非小细胞肺癌患者的安全性和有效性的 I 期临床试验

Blumenschein, George R; Devarakonda, Siddhartha; Johnson, Melissa; Moreno, Victor; Gainor, Justin; Edelman, Martin J; Heymach, John V; Govindan, Ramaswamy; Bachier, Carlos; Doger de Spéville, Bernard; Frigault, Matthew J; Olszanski, Anthony J; Lam, Vincent K; Hyland, Natalie; Navenot, Jean-Marc; Fayngerts, Svetlana; Wolchinsky, Zohar; Broad, Robyn; Batrakou, Dzmitry; Pentony, Melissa M; Sanderson, Joseph P; Gerry, Andrew; Marks, Diane; Bai, Jane; Holdich, Tom; Norry, Elliot; Fracasso, Paula M

Phase 1 Clinical Trial Evaluating the Safety and Anti-Tumor Activity of ADP-A2M10 SPEAR T-Cells in Patients With MAGE-A10+ Head and Neck, Melanoma, or Urothelial Tumors

评估 ADP-A2M10 SPEAR T 细胞在 MAGE-A10+ 头颈部肿瘤、黑色素瘤或尿路上皮肿瘤患者中的安全性和抗肿瘤活性的 1 期临床试验

Hong, David S; Butler, Marcus O; Pachynski, Russell K; Sullivan, Ryan; Kebriaei, Partow; Boross-Harmer, Sarah; Ghobadi, Armin; Frigault, Matthew J; Dumbrava, Ecaterina E; Sauer, Amy; Brophy, Francine; Navenot, Jean-Marc; Fayngerts, Svetlana; Wolchinsky, Zohar; Broad, Robyn; Batrakou, Dzmitry G; Wang, Ruoxi; Solis, Luisa M; Duose, Dzifa Yawa; Sanderson, Joseph P; Gerry, Andrew B; Marks, Diane; Bai, Jane; Norry, Elliot; Fracasso, Paula M

Newly developed pseudogout arthritis after therapy with MAGE-A4 directed TCR T cells responded to treatment with tocilizumab

接受 MAGE-A4 靶向 TCR T 细胞治疗后新出现的假性痛风性关节炎对托珠单抗治疗有反应

Sang T Kim ,Jean Tayar ,Siqing Fu ,Danxia Ke ,Elliot Norry ,Amy Sun ,Juli Miller ,David S Hong

Heat knockdown resistance and chill-coma recovery as correlated responses to selection on mating success at high temperature in Drosophila buzzatii

果蝇(Drosophila buzzatii)的耐热性和冷昏迷恢复能力与高温下交配成功率的选择呈正相关

Stazione, Leonel; Norry, Fabian M; Gomez, Federico H; Sambucetti, Pablo

Tuning T-Cell Receptor Affinity to Optimize Clinical Risk-Benefit When Targeting Alpha-Fetoprotein-Positive Liver Cancer

调整 T 细胞受体亲和力以优化针对甲胎蛋白阳性肝癌的临床风险收益

Roslin Y Docta, Tiago Ferronha, Joseph P Sanderson, Thomas Weissensteiner, George R Pope, Alan D Bennett, Nicholas J Pumphrey, Zoltan Ferjentsik, Laura L Quinn, Guy E Wiedermann, Victoria E Anderson, Manoj Saini, Miguel Maroto, Elliot Norry, Andrew B Gerry

Quantitative Trait Loci and Antagonistic Associations for Two Developmentally Related Traits in the Drosophila Head

果蝇头部两个发育相关性状的数量性状基因座及其拮抗关联

Norry, Fabian M; Gomez, Federico H

Characterisation of liver chemistry abnormalities associated with pazopanib monotherapy: a systematic review and meta-analysis of clinical trials in advanced cancer patients

帕唑帕尼单药治疗相关肝功能异常的特征分析:晚期癌症患者临床试验的系统评价和荟萃分析

Powles, Thomas; Bracarda, Sergio; Chen, Mei; Norry, Elliot; Compton, Natalie; Heise, Mark; Hutson, Thomas; Harter, Philipp; Carpenter, Christopher; Pandite, Lini; Kaplowitz, Neil