日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CUT&Tag recovers up to half of ENCODE ChIP-seq histone acetylation peaks.

CUT&Tag 可恢复高达一半的 ENCODE ChIP-seq 组蛋白乙酰化峰

Abbasova Leyla, Urbanaviciute Paulina, Hu Di, Ismail Joy N, Schilder Brian M, Nott Alexi, Skene Nathan G, Marzi Sarah J

Integrated multi-omic characterizations of the synapse reveal RNA processing factors and ubiquitin ligases associated with neurodevelopmental disorders.

对突触进行综合多组学表征,揭示了与神经发育障碍相关的 RNA 加工因子和泛素连接酶

Mei Yuan, Gosztyla Maya L, Tan Xinzhu, Dozier Lara E, Wilkinson Brent, McKetney Justin, Lee John, Chen Michael, Tsai Dorothy, Kopalle Hema, Gritsenko Marina A, Hartel Nicolas, Graham Nicholas A, Flores Ilse, Gilmore-Hall Stephen K, Xu Shuhao, Marquez Charlotte A, Liu Sophie N, Fong Dylan, Chen Jing, Licon Kate, Hong Derek, Wright Sarah N, Kreisberg Jason F, Nott Alexi, Smith Richard D, Qian Wei-Jun, Swaney Danielle L, Iakoucheva Lilia M, Krogan Nevan J, Patrick Gentry N, Zhou Yang, Feng Guoping, Coba Marcelo P, Yeo Gene W, Ideker Trey

CHAS infers cell type-specific signatures in bulk brain histone acetylation studies of neurological and psychiatric disorders

CHAS通过对神经和精神疾病患者脑组织组蛋白乙酰化水平的分析,推断出细胞类型特异性特征。

Murphy, Kitty B; Ye, Yuqian; Tsalenchuk, Maria; Nott, Alexi; Marzi, Sarah J

Genetic risk for neurodegenerative conditions is linked to disease-specific microglial pathways

神经退行性疾病的遗传风险与疾病特异性的小胶质细胞通路有关。

Askarova, Aydan; Yaa, Reuben M; Marzi, Sarah J; Nott, Alexi

Genetic insights into immune mechanisms of Alzheimer's and Parkinson's disease

阿尔茨海默病和帕金森病免疫机制的遗传学见解

Nott, Alexi; Holtman, Inge R

Brain cell type-specific enhancer-promoter interactome maps and disease-risk association

脑细胞类型特异性增强子-启动子相互作用组图谱及其与疾病风险的关联

Nott, Alexi; Holtman, Inge R; Coufal, Nicole G; Schlachetzki, Johannes C M; Yu, Miao; Hu, Rong; Han, Claudia Z; Pena, Monique; Xiao, Jiayang; Wu, Yin; Keulen, Zahara; Pasillas, Martina P; O'Connor, Carolyn; Nickl, Christian K; Schafer, Simon T; Shen, Zeyang; Rissman, Robert A; Brewer, James B; Gosselin, David; Gonda, David D; Levy, Michael L; Rosenfeld, Michael G; McVicker, Graham; Gage, Fred H; Ren, Bing; Glass, Christopher K

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development

NuRD染色质重塑复合物亚基的功能转换调控小鼠皮层发育

Nitarska, Justyna; Smith, Jacob G; Sherlock, William T; Hillege, Michele M G; Nott, Alexi; Barshop, William D; Vashisht, Ajay A; Wohlschlegel, James A; Mitter, Richard; Riccio, Antonella

CLONAL EVOLUTION OF GLIOMAS IS ENCODED IN THE EVOLUTIONARY DYNAMICS OF DNA METHYLATION

胶质瘤的克隆进化编码于DNA甲基化的进化动力学中

Nott, Alexi; Cho, Sukhee; Seo, Jinsoo; Tsai, Li-Huei; Costello, Joseph F; Mazor, Tali; Pankov, Alex; Johnson, Brett E; Hong, Chibo; Bell, Robert JA; Smirnov, Ivan V; Reis, Gerald F; Phillips, Joanna J; Barnes, Michael; Bollen, Andrew W; Taylor, Barry S; Molinaro, Annette M; Olshen, Adam B; Song, Jun S; Berger, Mitchel S; Chang, Susan M; Costello, Joseph F

S-nitrosylation of HDAC2 regulates the expression of the chromatin-remodeling factor Brm during radial neuron migration.

HDAC2 的 S-亚硝基化调节放射状神经元迁移过程中染色质重塑因子 Brm 的表达

Nott Alexi, Nitarska Justyna, Veenvliet Jesse V, Schacke Stephan, Derijck Alwin A H A, Sirko Piotr, Muchardt Christian, Pasterkamp R Jeroen, Smidt Marten P, Riccio Antonella