文献库，生知库 | 链接生命科学的每一步

日期影响因子

Combining Directed Evolution with Machine Learning Enables Accurate Genotype-to-Phenotype Predictions

将定向进化与机器学习相结合，可以实现准确的基因型到表型预测。

doi:10.1101/2025.01.27.635131

Howard, Alexander J; Rim, Ellen Y; Garrett, Oscar D; Shim, Yejin; Notwell, James H; Ronald, Pamela C

发表日期：2025

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Transcription factor expression defines subclasses of developing projection neurons highly similar to single-cell RNA-seq subtypes

转录因子表达定义了发育中的投射神经元的亚类，与单细胞 RNA 测序亚型高度相似

期刊:Proceedings of the National Academy of Sciences of the United States of America

doi:10.1073/pnas.2008013117

Whitney E Heavner, Shaoyi Ji, James H Notwell, Ethan S Dyer, Alex M Tseng, Johannes Birgmeier, Boyoung Yoo, Gill Bejerano, Susan K McConnell0

发表日期：2020

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A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human

对高度保守的非编码 GWAS SNP 进行筛查，发现 MIR-9-2 功能突变与人类视网膜血管缺陷相关。

期刊:Nucleic Acids Research

影响因子:13.1

doi:10.1093/nar/gky166

Madelaine, Romain; Notwell, James H; Skariah, Gemini; Halluin, Caroline; Chen, Charles C; Bejerano, Gill; Mourrain, Philippe

发表日期：2018

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A Guide to Single-Cell Transcriptomics in Adult Rodent Brain: The Medium Spiny Neuron Transcriptome Revisited

成年啮齿动物脑单细胞转录组学指南：中型棘状神经元转录组再探

期刊:Frontiers in Cellular Neuroscience

影响因子:4.2

doi:10.3389/fncel.2018.00159

Hanson Ho ,Matt De Both ,Ashley Siniard ,Sasha Sharma ,James H Notwell ,Michelle Wallace ,Dino P Leone ,Amy Nguyen ,Eric Zhao ,Hannah Lee ,Daniel Zwilling ,Kimberly R Thompson ,Steven P Braithwaite ,Matthew Huentelman ,Thomas Portmann

细胞生物学

发表日期：2018

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MicroRNA-9 Couples Brain Neurogenesis and Angiogenesis

microRNA-9 连接脑神经发生和血管生成

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2017.07.051

Madelaine, Romain; Sloan, Steven A; Huber, Nina; Notwell, James H; Leung, Louis C; Skariah, Gemini; Halluin, Caroline; Paşca, Sergiu P; Bejerano, Gill; Krasnow, Mark A; Barres, Ben A; Mourrain, Philippe

发表日期：2017

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TBR1 regulates autism risk genes in the developing neocortex

TBR1 调控发育中的新皮质中的自闭症风险基因

期刊:Genome Research

影响因子:6.2

doi:10.1101/gr.203612.115

James H Notwell, Whitney E Heavner, Siavash Fazel Darbandi, Sol Katzman, William L McKenna, Christian F Ortiz-Londono, David Tastad, Matthew J Eckler, John L R Rubenstein, Susan K McConnell, Bin Chen, Gill Bejerano

发表日期：2016

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A family of transposable elements co-opted into developmental enhancers in the mouse neocortex

小鼠新皮层中一类转座元件被利用来增强发育功能

期刊:Nature Communications

影响因子:15.7

doi:10.1038/ncomms7644

Notwell, James H; Chung, Tisha; Heavner, Whitney; Bejerano, Gill

发育与干细胞

发表日期：2015

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