日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Immediate or high-dose antituberculosis therapy for HIV-related sepsis in Tanzania and Uganda (ATLAS): a phase 3, open-label, randomised, controlled, 2 × 2 factorial, superiority trial

在坦桑尼亚和乌干达开展的针对 HIV 相关脓毒症的即刻或高剂量抗结核治疗(ATLAS):一项 3 期、开放标签、随机、对照、2 × 2 析因设计、优效性试验

Heysell, Scott K; Mpagama, Stellah G; Nuwagira, Edwin; Said, Bibie; Conaway, Mark; Null, Megan; Thomas, Tania A; Boulware, David R; Otoupalova, Eva; Arinaitwe, Rinah; Mushagara, Rhina; Edwards, Louisa; Buzaare, Peter; Ngoma, Athumani M; Muganzi, Davis; Gidoi, Geofrey; Jjunju, Samuel; Gulinja, Antony; Rimoy, Arestaricky G; Mwita, Fredrick C; Kidola, Jeremiah; Atwiine, Oscar; Ocaaki, David; Munyambalu, Dalton K; Liu, Jie; Ampaire, Lucas; Mujaga, Buliga; Rao, Prakruti; Liyoyo, Alphonce; Sariko, Margaretha; Muzoora, Conrad; Moore, Christopher C

Aetiology of sepsis in adults living with HIV in East Africa: a secondary analysis of an open-label, multicentre, randomised, controlled phase 3 trial

东非地区艾滋病毒感染成人脓毒症的病因:一项开放标签、多中心、随机、对照的3期试验的二次分析

Otoupalova, Eva; Ampaire, Lucas; Null, Megan; Mujaga, Buliga; Liu, Jie; Said, Bibie; Nuwagira, Edwin; Sariko, Margaretha; Gidoi, Geofrey; Gulinja, Antony; Jjunju, Samuel; Rimoy, Arestaricky; Mwita, Fredrick C; Kidola, Jeremiah; Atwiine, Oscar; Ocaaki, David; Munyambalu, Dalton K; Rao, Prakruti; Boulware, David R; Thomas, Tania A; Mpagama, Stellah; Muzoora, Conrad; Heysell, Scott K; Moore, Christopher C

RAREsim2: Flexible simulation of rare variant genetic data using real haplotypes

RAREsim2:利用真实单倍型灵活模拟罕见变异遗传数据

Murphy, Jessica I; Barnard, Ryan; Null, Megan; Hendricks, Audrey E

A narrative review of the pathophysiology of sepsis in sub-Saharan Africa: Exploring the potential for corticosteroid therapy

对撒哈拉以南非洲脓毒症病理生理学的叙述性综述:探索皮质类固醇治疗的潜力

Gruccio, Phoebe; Girard, William S; Badipour, Amelia D; Kakande, Reagan; Adejayan, Victor; Zulfiqar, Muhammad; Ndyomugabe, Michael; Ojuman, Philemon; Heysell, Scott K; Null, Megan; Sturek, Jeffrey; Thomas, Tania; Mpagama, Stellah; Muzoora, Conrad; Otoupalova, Eva; Nuwagira, Edwin; Moore, Christopher C

Immune subphenotypes of tuberculosis and mortality in adults with sepsis and a high prevalence of HIV in East Africa

东非地区结核病免疫亚表型与脓毒症成人死亡率及艾滋病毒感染率高发人群的关系

Edwards, Louisa; Jacob, Shevin T; Majwala, Albert; Banura, Patrick; Heysell, Scott K; Mpagama, Stellah; Null, Megan; Thomas, Tania A; Rimoy, Arestaricky; Said, Bibie; Nuwagira, Edwin; Muzoora, Conrad; Sturek, Jeffrey M; Moore, Christopher C; Otoupalova, Eva

Human Neonatal MR1T Cells Have Diverse TCR Usage, are Less Cytotoxic and are Unable to Respond to Many Common Childhood Pathogens

人类新生儿MR1T细胞具有多种TCR使用模式,细胞毒性较低,且无法对许多常见的儿童病原体产生反应。

Kain, Dylan; Awad, Wael; McElfresh, G W; Cansler, Meghan; Swarbrick, Gwendolyn M; Poa, Kean Chan Yew; McNeice, Conor; Boggy, Gregory; Rott, Katherine; Null, Megan D; Lewinsohn, David M; Rossjohn, Jamie; Bimber, Benjamin N; Lewinsohn, Deborah A

The Universal Vital Assessment (UVA) score at 6 hours post-resuscitation predicts mortality in hospitalized adults with severe sepsis in Mbarara, Uganda

在乌干达姆巴拉拉,复苏后6小时的通用生命体征评估(UVA)评分可以预测住院重症脓毒症成年患者的死亡率。

Null, Megan; Conaway, Mark; Hazard, Riley; Edwards, Louisa; Taseera, Kabanda; Muhindo, Rose; Olum, Sam; Mbonde, Amir Abdallah; Moore, Christopher C

Production of Proinflammatory Cytokines by CD4+ and CD8+ T Cells in Response to Mycobacterial Antigens among Children and Adults with Tuberculosis

结核病患儿和成人中 CD4+ 和 CD8+ T 细胞对分枝杆菌抗原产生促炎细胞因子的反应

Morrow, Erin; Liu, Qijia; Kiguli, Sarah; Swarbrick, Gwendolyn; Nsereko, Mary; Null, Megan D; Cansler, Meghan; Mayanja-Kizza, Harriet; Boom, W Henry; Chheng, Phalkun; Nyendak, Melissa R; Lewinsohn, David M; Lewinsohn, Deborah A; Lancioni, Christina L

RAREsim: A simulation method for very rare genetic variants

RAREsim:一种模拟极罕见遗传变异的方法

Null, Megan; Dupuis, Josée; Sheinidashtegol, Pezhman; Layer, Ryan M; Gignoux, Christopher R; Hendricks, Audrey E

Deaza-modification of MR1 ligands modulates recognition by MR1-restricted T cells

MR1配体的脱氮修饰调节MR1限制性T细胞的识别

Jin, Haihong; Ladd, Nicole A; Peev, Andrew M; Swarbrick, Gwendolyn M; Cansler, Meghan; Null, Megan; Boughter, Christopher T; McMurtrey, Curtis; Nilsen, Aaron; Dobos, Karen M; Hildebrand, William H; Lewinsohn, Deborah A; Adams, Erin J; Lewinsohn, David M; Harriff, Melanie J