日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Sequential structural rearrangements at the PAM-distal site of a type I-F3 CRISPR-Cas effector enabling RNA-guided DNA transposition

I型F3 CRISPR-Cas效应蛋白PAM远端位点的序列结构重排可实现RNA引导的DNA转座

Ishihara, Kazuki; Matsumoto, Shunsuke; Gerle, Christoph; Gopalasingam, Chai C; Shigematsu, Hideki; Shirai, Tsuyoshi; Numata, Tomoyuki

Substrate specificity and action mechanism of the HerA-NurA nuclease from the hyperthermophilic archaeon Thermococcus kodakarensis

来自嗜热古菌科达卡氏热球菌(Thermococcus kodakarensis)的HerA-NurA核酸酶的底物特异性和作用机制

Uda, Keishiro; Yamagami, Takeshi; Ishino, Sonoko; Gerle, Christoph; Gopalasingam, Chai C; Shigematsu, Hideki; Numata, Tomoyuki; Ishino, Yoshizumi

Msp1 and Pex19-Pex3 cooperate to achieve correct localization of Pex15 to peroxisomes.

Msp1 和 Pex19-Pex3 协同作用,使 Pex15 正确定位到过氧化物酶体

Matsumoto Shunsuke, Kogure Yoshiki, Ono Suzuka, Numata Tomoyuki, Endo Toshiya

Mechanistic analysis of Riboswitch Ligand interactions provides insights into pharmacological control over gene expression

对核糖开关配体相互作用的机制分析为基因表达的药理学调控提供了新的见解

Parmar, Shaifaly; Bume, Desta Doro; Connelly, Colleen M; Boer, Robert E; Prestwood, Peri R; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth, John S Jr

Mechanistic Analysis of Riboswitch Ligand Interactions Provides Insights into Pharmacological Control over Gene Expression

核糖开关配体相互作用的机制分析为基因表达的药理学调控提供了新的见解

Parmar, Shaifaly; Bume, Desta Doro; Conelly, Colleen; Boer, Robert; Prestwood, Peri R; Wang, Zhen; Labuhn, Henning; Sinnadurai, Krishshanthi; Feri, Adeline; Ouellet, Jimmy; Homan, Philip; Numata, Tomoyuki; Schneekloth, John S Jr

Minimal protein-only RNase P structure reveals insights into tRNA precursor recognition and catalysis

仅包含蛋白质的最小 RNase P 结构揭示了 tRNA 前体识别和催化的机制

Teramoto, Takamasa; Koyasu, Takeshi; Adachi, Naruhiko; Kawasaki, Masato; Moriya, Toshio; Numata, Tomoyuki; Senda, Toshiya; Kakuta, Yoshimitsu

Synthetic ligands for PreQ(1) riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure

PreQ(1)核糖开关的合成配体为靶向RNA三级结构提供了结构和机制方面的见解。

Connelly, Colleen M; Numata, Tomoyuki; Boer, Robert E; Moon, Michelle H; Sinniah, Ranu S; Barchi, Joseph J; Ferré-D'Amaré, Adrian R; Schneekloth, John S Jr

Crystallization and preliminary X-ray diffraction analysis of the CRISPR-Cas RNA-silencing Cmr complex

CRISPR-Cas RNA沉默复合物Cmr的结晶和初步X射线衍射分析

Osawa, Takuo; Inanaga, Hideko; Numata, Tomoyuki

Crystallization and preliminary X-ray diffraction analysis of the Cmr2-Cmr3 subcomplex in the CRISPR-Cas RNA-silencing effector complex

CRISPR-Cas RNA沉默效应复合物中Cmr2-Cmr3亚复合物的结晶和初步X射线衍射分析

Osawa, Takuo; Inanaga, Hideko; Numata, Tomoyuki

Crystallization and preliminary X-ray diffraction analysis of an active-site mutant of `loopless' family GH19 chitinase from Bryum coronatum in a complex with chitotetraose

对来自冠状藓(Bryum coronatum)的“无环”GH19家族几丁质酶活性位点突变体与壳四糖复合物的结晶和初步X射线衍射分析

Ohnuma, Takayuki; Umemoto, Naoyuki; Taira, Toki; Fukamizo, Tamo; Numata, Tomoyuki