日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

单层跨膜细胞色素P450的结构表明,其催化结构域相对于双层膜的方向受到限制。

Monk, Brian C; Tomasiak, Thomas M; Keniya, Mikhail V; Huschmann, Franziska U; Tyndall, Joel D A; O'Connell, Joseph D 3rd; Cannon, Richard D; McDonald, Jeffrey G; Rodriguez, Andrew; Finer-Moore, Janet S; Stroud, Robert M

Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells.

对靶向肿瘤细胞的新型胸苷酸合成酶抑制剂 N-[4-[2-丙炔-1-基[(6S)-4,6,7,8-四氢-2-(羟甲基)-4-氧代-3H-环戊并[g]喹唑啉-6-基]氨基]苯甲酰基]-l-γ-谷氨酰-D-谷氨酸 (BGC 945) 进行开发和结合模式评估

Tochowicz Anna, Dalziel Sean, Eidam Oliv, O'Connell Joseph D 3rd, Griner Sarah, Finer-Moore Janet S, Stroud Robert M

Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening

通过快速表达和溶解筛选,选择用于结构测定的最佳真核生物整合膜蛋白。

Li, Min; Hays, Franklin A; Roe-Zurz, Zygy; Vuong, Linda; Kelly, Libusha; Ho, Chi-Min; Robbins, Renée M; Pieper, Ursula; O'Connell, Joseph D 3rd; Miercke, Larry J W; Giacomini, Kathleen M; Sali, Andrej; Stroud, Robert M

Architecture and selectivity in aquaporins: 2.5 a X-ray structure of aquaporin Z

水通道蛋白的结构和选择性:2.5 水通道蛋白 Z 的 X 射线结构

Savage, David F; Egea, Pascal F; Robles-Colmenares, Yaneth; O'Connell, Joseph D 3rd; Stroud, Robert M