日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Identification of a series of pyrrolo-pyrimidine-based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication

鉴定出一系列基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂,这些抑制剂能够抑制冠状病毒的复制

Pfannenstiel, Jessica J; Duong, Men Thi Hoai; Cluff, Daniel; Sherrill, Lavinia M; Colquhoun, Iain; Cadoux, Gabrielle; Thorne, Devyn; Pääkkönen, Johan; Schemmel, Nathaniel F; O'Connor, Joseph; Saenjamsai, Pradtahna; Feng, Mei; Parthasarathy, Srivatsan; Hageman, Michael J; Johnson, David K; Roy, Anuradha; Lehtiö, Lari; Ferraris, Dana V; Fehr, Anthony R

IFN-γ signaling is required for the efficient replication of murine hepatitis virus (MHV) strain JHM in the brains of infected mice

IFN-γ信号传导是鼠肝炎病毒(MHV)JHM株在感染小鼠脑内有效复制所必需的。

Kerr, Catherine M; Proctor-Roser, Macie A; Parthasarathy, Srivatsan; O'Connor, Joseph J; Pfannenstiel, Jessica J; Orozco, Robin C; Fehr, Anthony R

Mutation of a highly conserved isoleucine residue in loop 2 of several β-coronavirus macrodomains indicates that enhanced ADP-ribose binding is detrimental for replication

多个β冠状病毒宏结构域2环中高度保守的异亮氨酸残基的突变表明,增强的ADP-核糖结合不利于病毒复制。

Kerr, Catherine M; Pfannenstiel, Jessica J; Alhammad, Yousef M; O'Connor, Joseph J; Ghimire, Roshan; Shrestha, Rakshya; Khattabi, Reem; Saenjamsai, Pradtahna; Parthasarathy, Srivatsan; McDonald, Peter R; Gao, Philip; Johnson, David K; More, Sunil; Roy, Anuradha; Channappanavar, Rudragouda; Fehr, Anthony R

Clinical expression of programmed maxillary buccal expansion and buccolingual crown inclination with Invisalign EX30 and SmartTrack aligners and the effect of 1-week vs. 2-week aligner change regimes: A retrospective cohort study

Invisalign EX30 和 SmartTrack 矫正器在上颌颊侧扩张和颊舌向牙冠倾斜度方面的临床表现,以及 1 周与 2 周矫正器更换方案的效果:一项回顾性队列研究

O'Connor, Joseph; Weir, Tony; Freer, Elissa; Kerr, Brett

Identification of a series of pyrrolo-pyrimidine based SARS-CoV-2 Mac1 inhibitors that repress coronavirus replication.

鉴定出一系列基于吡咯并嘧啶的SARS-CoV-2 Mac1抑制剂,这些抑制剂能够抑制冠状病毒的复制

Pfannenstiel Jessica J, Duong Men Thi Hoai, Cluff Daniel, Sherrill Lavania M, Colquhoun Iain, Cadoux Gabrielle, Thorne Devyn, Pääkkönen Johan, Schemmel Nathaniel F, O'Connor Joseph, Saenjamsai Pradtahna, Feng Mei, Hageman Michael J, Johnson David K, Roy Anuradha, Lehtiö Lari, Ferraris Dana V, Fehr Anthony R

Matrix metalloproteinase-3 (MMP-3)-mediated gene therapy for glaucoma

基质金属蛋白酶-3(MMP-3)介导的青光眼基因治疗

Jeffrey O'Callaghan, Conor Delaney, Merissa O'Connor, Joseph van Batenburg-Sherwood, Martin Schicht, Elke Lütjen-Drecoll, Natalie Hudson, Sorcha Ni Dhubhghaill, Peter Humphries, Chris Stanley, Annahita Keravala, Thomas Chalberg, Matthew S Lawrence, Matthew Campbell

Two Commercially Available Blood-Stabilization Reagents Serve as Potent Inactivators of Coronaviruses

两种市售血液稳定剂可作为冠状病毒的有效灭活剂

O'Connor, Joseph J; Voth, Lynden; Athmer, Jeremiah; George, Nicholas M; Connelly, Christopher M; Fehr, Anthony R

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

减少体外培养可提高嵌合抗原受体(CAR)T细胞的抗白血病活性

Saba Ghassemi ,Selene Nunez-Cruz ,Roddy S O'Connor ,Joseph A Fraietta ,Prachi R Patel ,John Scholler ,David M Barrett ,Stefan M Lundh ,Megan M Davis ,Felipe Bedoya ,Changfeng Zhang ,John Leferovich ,Simon F Lacey ,Bruce L Levine ,Stephan A Grupp ,Carl H June ,J Joseph Melenhorst # ,Michael C Milone #

Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer

TGFβ诱导的上皮-间质转化生物力学:对纤维化和癌症的影响

O'Connor, Joseph W; Gomez, Esther W

Cobalt 1,3-Diisopropyl-1H-imidazol-2-ylidene Complexes: Synthesis, Solid-State Structures, and Quantum Chemistry Calculations

钴 1,3-二异丙基-1H-咪唑-2-亚基配合物:合成、固态结构和量子化学计算

Vélez, Carmen L; Markwick, Phineus R L; Holland, Ryan L; Dipasquale, Antonio G; Rheingold, Arnold L; O'Connor, Joseph M