日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer Treated With Cyclin-Dependent Kinase 4/6 Inhibitors

真实世界中,接受细胞周期蛋白依赖性激酶 4/6 抑制剂治疗的高危和转移性激素受体阳性、人表皮生长因子受体 2 阴性乳腺癌患者的血浆胸苷激酶活性

O'Connor, Thomas N; Schultz, Emily; Kabraji, Sheheryar; Levine, Ellis; Williams, Amy J; Knudsen, Erik S; Witkiewicz, Agnieszka K

Acquired resistance in cancer: towards targeted therapeutic strategies

癌症获得性耐药:迈向靶向治疗策略

Soragni, Alice; Knudsen, Erik S; O'Connor, Thomas N; Tognon, Cristina E; Tyner, Jeffrey W; Gini, Beatrice; Kim, Donghwa; Bivona, Trever G; Zang, Xingxing; Witkiewicz, Agnieszka K; Goodrich, David W; Jiang, Dadi; Gammon, Seth T; Willey, Christopher D; Boutros, Paul C; Sandulache, Vlad C; Osman, Abdullah A; Myers, Jeffrey N; Mehla, Kamiya; Singh, Pankaj K; Chan, Keith S; Gao, Hongbo; Marathe, Himangi

Tumor Suppressors Condition Differential Responses to the Selective CDK2 Inhibitor BLU-222.

肿瘤抑制因子对选择性 CDK2 抑制剂 BLU-222 的反应存在差异

Dommer Adam P, Kumarasamy Vishnu, Wang Jianxin, O'Connor Thomas N, Roti Michelle, Mahan Sidney, McLean Karen, Knudsen Erik S, Witkiewicz Agnieszka K

Intrinsic RB activation induces tumoral and stromal anti-tumor responses that limit triple-negative breast cancer.

内在的 RB 激活诱导肿瘤和基质抗肿瘤反应,从而限制三阴性乳腺癌。

Wan Yin, Wang Jianxin, O'Connor Thomas N, Kumarasamy Vishnu, Sanidas Ioannis, Abrams Scott I, Witkiewicz Agnieszka K, Knudsen Erik S

Using prognostic signatures and machine learning to identify core features associated with response to CDK4/6 inhibitor-based therapy in metastatic breast cancer

利用预后特征和机器学习来识别与转移性乳腺癌对 CDK4/6 抑制剂疗法的反应相关的核心特征

Witkiewicz, Agnieszka K; Wang, Jianxin; Schultz, Emily; O'Connor, Thomas N; O'Connor, Tracey; Levine, Ellis; Knudsen, Erik S

Voluntary Wheel Running Mitigates Disease in an Orai1 Gain-of-Function Mouse Model of Tubular Aggregate Myopathy.

自愿轮跑可减轻 Orai1 功能获得性小鼠管状聚集肌病模型中的疾病

O'Connor Thomas N, Zhao Nan, Orciuoli Haley M, Malik Sundeep, Brasile Alice, Pietrangelo Laura, He Miao, Groom Linda, Leigh Jennifer, Mahamed Zahra, Liang Chen, Protasi Feliciano, Dirksen Robert T

Cell Cycle Plasticity and Heterogeneity: An Underappreciated Feature of Cancer and Treatment Response

细胞周期可塑性和异质性:癌症及其治疗反应中一个被低估的特征

Knudsen, Erik S; O'Connor, Thomas N; Witkiewicz, Agnieszka K

Cortical microglia dynamics are conserved during voluntary wheel running

自愿轮跑运动期间,皮层小胶质细胞的动力学保持不变。

Strohm, Alexandra O; O'Connor, Thomas N; Oldfield, Sadie; Young, Sala; Hammond, Christian; McCall, Matthew; Dirksen, Robert T; Majewska, Ania K