Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity
结肠支配传入神经上的致痒因子TGR5、MrgprA3和MrgprC11的激活可诱发内脏高敏感性。
期刊:JCI Insight
影响因子:6.1
doi:10.1172/jci.insight.131712
Castro, Joel; Harrington, Andrea M; Lieu, TinaMarie; Garcia-Caraballo, Sonia; Maddern, Jessica; Schober, Gudrun; O'Donnell, Tracey; Grundy, Luke; Lumsden, Amanda L; Miller, Paul; Ghetti, Andre; Steinhoff, Martin S; Poole, Daniel P; Dong, Xinzhong; Chang, Lin; Bunnett, Nigel W; Brierley, Stuart M