日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Long-acting GIPR agonist LY3537021 reduces body weight and fasting blood glucose in patients with T2D: Preclinical development and phase 1 randomized ascending dose studies

长效GIPR激动剂LY3537021可降低2型糖尿病患者的体重和空腹血糖:临床前开发和1期随机递增剂量研究

Roell, William; Alsina-Fernandez, Jorge; Qu, Hongchang; Coskun, Tamer; Benson, Charles; Haupt, Axel; Kelly, Ronan P; O'Farrell, Libbey; Sloop, Kyle W; Steele, James P; Ficorilli, James; Regmi, Ajit; Rettiganti, Mallikarjuna; Urva, Shweta; Mather, Kieren J; Pratt, Edward

IFN-γ-induced trained immunity enhances killing of priority pathogens in healthy and genetically vulnerable individuals.

IFN-γ诱导的训练免疫可增强健康个体和遗传易感个体对重点病原体的杀灭作用。

Murphy Dearbhla M, Batten Isabella, O'Farrell Aoife, Carlile Simon R, O'Rourke Sinead A, Court Chloe, Morris Brenda, Leisching Gina, Jameson Gráinne, Connolly Sarah A, Dyer Adam H, McGrath John P, McNally Emma, Sandby-Thomas Olivia, Yennemadi Anjali, Finlay Conor M, Cheallaigh Clíona Ní, Dunne Jean, Maoldomhnaigh Cilian Ó, Gleeson Laura E, Dunne Aisling, Bourke Nollaig, van Crevel Reinout, Cox Donal J, Conlon Niall, Raj Arjun, McLoughlin Rachel M, Keane Joseph, Basdeo Sharee A

GLP-1R biased cAMP agonism maintains glycemic control with reduced malaise and emesis in preclinical mammalian models

在临床前哺乳动物模型中,GLP-1R 偏向性 cAMP 激动剂作用可维持血糖控制,并减少不适和呕吐。

Baumer-Harrison, Caitlin; Aldaghma, Danya; White, Alex D; Applebey, Sarah V; Pataro, Allison M; Mohiby, Allaha Z; Alonso, Brandon; Xiao, Allison G; O'Farrell, Libbey S; Qian, Yuewei; Coskun, Tamer; Coghlan, Matthew P; Willard, Francis S; Ai, Minrong; Sloop, Kyle W; Doyle, Robert P; Borner, Tito; De Jonghe, Bart C; Hayes, Matthew R

Barriers and Facilitators to Timely Adjuvant Therapy for Head and Neck Cancer in Rural Care

农村地区头颈癌患者及时接受辅助治疗的障碍和促进因素

Wasp, Garrett T; Khudaier, Shahed; Siroonian, Olivia; Coogan, Michelle E C; Anton, Catherine; Fortuna, Karen L; Papas, Stephanie; Skrypeck, Rebecca; Wing, Lucia; O'Farrell, Justin; Divakar, Prashanthi; Schaner, Philip E

Neutrophil-related gene expression profile is associated with future paediatric bronchiectasis exacerbations

中性粒细胞相关基因表达谱与未来儿童支气管扩张症急性加重有关

O'Farrell, Hannah E; Goyal, Vikas; Chang, Anne B; Grimwood, Keith; Cheng, Michael; Yerkovich, Stephanie T; Baines, Katherine J

Improving asthma control assessment and outcomes in children with asthma using an artificial intelligence digital tool: a prospective multicentre cohort study

利用人工智能数字工具改善儿童哮喘控制评估和治疗效果:一项前瞻性多中心队列研究

Chang, Anne B; Yerkovich, Stephanie T; McPhail, Steven M; Selvadurai, Hiran; Goyal, Vikas; George, Shane; McCallum, Gabrielle B; Morris, Peter S; O'Farrell, Hannah; Versteegh, Lesley A; Grigg, Jonathan; McElrea, Margaret S; Worley, Sophie; Elliot-Holmes, Leanne; Yerkovich, Terase; Williams, Joanna; Grimwood, Keith; Marchant, Julie M

A pipeline of machine learning-driven multi-modal data fusion methods for prognostic risk analysis in bevacizumab-treated metastatic colorectal cancer

基于机器学习的多模态数据融合方法在贝伐珠单抗治疗的转移性结直肠癌预后风险分析中的应用

Thomas, Valentina; Nyamundanda, Gift; Lärkeryd, Adrian; Hari, P S; Miller, Ian S; Venken, Tom; Smeets, Dominiek; Boeckx, Bram; Betge, Johannes; Ebert, Matthias P A; Gaiser, Timo; Murphy, Verena; Kay, Elaine; Verheul, Henk M; O'Farrell, Alice C; Cremolini, Chiara; Marmorino, Federica; Gallagher, William M; Barat, Ana; Klinger, Rut; Fender, Bozena; Ylstra, Bauke; van Grieken, Nicole; McNamara, Deborah A; Hennessy, Bryan T; Das, Sudipto; Moran, Bruce; O'Connor, Darran P; Dienstmann, Rodrigo; Lambrechts, Diether; Prehn, Jochen H M; Sadanandam, Anguraj; Byrne, Annette T

Significance of nodal yield after rectal resection in the TNT era: does count matter?

TNT时代直肠切除术后淋巴结清扫数量的意义:计数重要吗?

O'Connell, L V; Murnaghan, N; O'Brien, A; Shields, C; Hogan, A; Cowzer, D; Aird, J; O'Farrell, N; Nugent, E; Rogers, A C

Caffeine and preterm infants: multiorgan effects and therapeutic creep: scope to optimise dose and timing

咖啡因与早产儿:多器官效应和治疗剂量递增:优化剂量和给药时间的空间。

O'Shea, Michael; Butler, Luke; Holohan, Sam; Healy, Kate; O'Farrell, Rebecca; Shamit, Amreena; Cusack, Ruth; Elhadi, Mai; Lynch, Sinead; Gilcrest, Megan; Semberova, Jana; Branagan, Aoife; O'Dea, Mary Isabel; Duddy, Peter; Ambalavanan, Namasivayam; Allegaert, Karel; Bearer, Cynthia F; Meehan, Judith; Molloy, Eleanor J

Real-World Use of Avatrombopag in Children and Adolescents With Immune Thrombocytopenia

阿伐曲波帕在儿童和青少年免疫性血小板减少症患者中的实际应用

Harris, Emily M; Montcrieff, Caitlin; O'Farrell, Candelaria; Konde, Praharsha; Lambert, Michele P; Grimes, Amanda B; Grace, Rachael F