日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Kinesin-1 conformational dynamics are controlled by a cargo-sensitive TPR switch

驱动蛋白-1的构象动力学受货物敏感的TPR开关控制。

Shukla, Shivam; Cross, Jessica A; Kish, Monika; Yadav, Sathish K N; Weijman, Johannes F; O'Regan, Laura; Mantell, Judith; Borucu, Ufuk; Leng, Xiyue; Schaffitzel, Christiane; Phillips, Jonathan J; Woolfson, Derek N; Dodding, Mark P

NEK7 phosphorylation of cortactin modulates the migratory capacity of cells expressing EML4-ALK V3.

NEK7 对 cortactin 的磷酸化调节表达 EML4-ALK V3 的细胞的迁移能力。

Richardson Emily L, Knebel Axel, Straatman Kees R, Gourlay Robert, Lamont Douglas, Hardy Tara, Turnbull Robert E, Robinson Susan W, O'Regan Laura, Bayliss Richard, Fry Andrew M

EML2 and EML4 splice variants regulate microtubule remodeling during neuronal cell differentiation.

EML2 和 EML4 剪接变体在神经元细胞分化过程中调节微管重塑

Marasi Venus, Adib Rozita, O'Regan Laura, Straatman Kees R, Prigent Sally A, Fry Andrew M

Alternative Treatment Options to ALK Inhibitor Monotherapy for EML4-ALK-Driven Lung Cancer

EML4-ALK驱动型肺癌的ALK抑制剂单药治疗替代方案

Papageorgiou, Savvas; Pashley, Sarah L; O'Regan, Laura; Khan, Sam; Bayliss, Richard; Fry, Andrew M

Novel insights into the mechanisms of mitotic spindle assembly by NEK kinases

NEK激酶介导的有丝分裂纺锤体组装机制的新见解

Prosser, Suzanna L; O'Regan, Laura; Fry, Andrew M

Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.

Nek7通过Nek9结合和诱导二聚化而被激活的机制基础

Haq Tamanna, Richards Mark W, Burgess Selena G, Gallego Pablo, Yeoh Sharon, O'Regan Laura, Reverter David, Roig Joan, Fry Andrew M, Bayliss Richard

Hsp70 proteins in mitosis and disease

有丝分裂和疾病中的Hsp70蛋白

O'Regan, Laura; Sampson, Josephina; Fry, Andrew M

Cell cycle regulation by the NEK family of protein kinases

NEK蛋白激酶家族对细胞周期的调控

Fry, Andrew M; O'Regan, Laura; Sabir, Sarah R; Bayliss, Richard

An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.

细胞周期调控的 Nek7 激酶中的自身抑制酪氨酸基序通过 Nek9 的结合而被释放

Richards Mark W, O'Regan Laura, Mas-Droux Corine, Blot Joelle M Y, Cheung Jack, Hoelder Swen, Fry Andrew M, Bayliss Richard

Mitotic regulation by NIMA-related kinases

NIMA相关激酶对有丝分裂的调控

O'regan, Laura; Blot, Joelle; Fry, Andrew M