日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Altered balance between Th17 and Th1 cells at mucosal sites predicts AIDS progression in simian immunodeficiency virus-infected macaques.

粘膜部位 Th17 细胞和 Th1 细胞平衡的改变可预测感染猴免疫缺陷病毒的猕猴的艾滋病进展

Cecchinato V, Trindade C J, Laurence A, Heraud J M, Brenchley J M, Ferrari M G, Zaffiri L, Tryniszewska E, Tsai W P, Vaccari M, Parks R Washington, Venzon D, Douek D C, O'Shea J J, Franchini G

Targeting the Jak/STAT pathway for immunosuppression

靶向JAK/STAT通路进行免疫抑制

O'shea, J J

T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells.

T-bet 在淋巴细胞和髓系细胞中可被干扰素-γ 迅速诱导表达

Lighvani A A, Frucht D M, Jankovic D, Yamane H, Aliberti J, Hissong B D, Nguyen B V, Gadina M, Sher A, Paul W E, O'Shea J J

Jaks and stats as therapeutic targets

JAKS 和 STATS 作为治疗靶点

O'Shea, J J; Visconti, R; Cheng, T P; Gadina, M

Janus kinases and signal transducers and activators of transcription: their roles in cytokine signaling, development and immunoregulation

Janus激酶和信号转导及转录激活因子:它们在细胞因子信号传导、发育和免疫调节中的作用

Ortmann, R A; Cheng, T; Visconti, R; Frucht, D M; O'Shea, J J

Autosomal SCID caused by a point mutation in the N-terminus of Jak3: mapping of the Jak3-receptor interaction domain

由Jak3 N端点突变引起的常染色体SCID:Jak3-受体相互作用域的定位

Cacalano, N A; Migone, T S; Bazan, F; Hanson, E P; Chen, M; Candotti, F; O'Shea, J J; Johnston, J A

Jak3 activation in human lymphocyte precursor cells

人类淋巴细胞前体细胞中的 Jak3 激活

Sharfe, N; Dadi, H K; O'Shea, J J; Roifman, C M

Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells

人类T细胞白血病病毒1型(HTLV-1)Tax蛋白或病毒转化细胞中不同JAK酪氨酸激酶的组成型激活

Xu, X; Kang, S H; Heidenreich, O; Okerholm, M; O'Shea, J J; Nerenberg, M I

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7

人单核细胞中JAK3表达的调控:白细胞介素2、4和7诱导的磷酸化

Musso, T; Johnston, J A; Linnekin, D; Varesio, L; Rowe, T K; O'Shea, J J; McVicar, D W

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12

白细胞介素 12 (IL-12) 诱导 JAK2 和 TYK2 的酪氨酸磷酸化:IL-2 和 IL-12 对 Janus 家族酪氨酸激酶的差异性利用

Bacon, C M; McVicar, D W; Ortaldo, J R; Rees, R C; O'Shea, J J; Johnston, J A