Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat
植入经基因工程改造可产生脑源性神经营养因子的成纤维细胞,可预防1-甲基-4-苯基吡啶对大鼠多巴胺能神经元的毒性作用。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.91.11.5104
Frim, D M; Uhler, T A; Galpern, W R; Beal, M F; Breakefield, X O; Isacson, O