日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

NKG2D upregulation sensitizes tumors to combined anti-PD1 and anti-VEGF therapy and prevents hearing loss

NKG2D 上调可增强肿瘤对联合抗 PD-1 和抗 VEGF 疗法的敏感性，并预防听力损失。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-68865-8
Lu, Simeng; Yin, Zhenzhen; Wu, Limeng; Sun, Yao; Chen, Jie; Wu, Lai Man Natalie; Oblinger, Janet L; Blake, Day C; Xiu, Bingyu; Landegger, Lukas D; Seist, Richard; Ho, William; Jones, Adam P; Muzikansky, Alona; Stankovic, Konstantina M; Plotkin, Scott R; Chang, Long-Sheng; Xu, Lei
肿瘤
肿瘤免疫
EGF
VEGF
PD-1
发表日期：2026
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Combining Brigatinib with mTOR Inhibition to Effectively Treat NF2-SWN-Associated and Sporadic NF2-Deficient Meningiomas

布加替尼联合 mTOR 抑制剂可有效治疗 NF2-SWN 相关和散发性 NF2 缺陷型脑膜瘤

期刊:Cancer Research Communications
影响因子:3.3
doi:10.1158/2767-9764.CRC-25-0563
Chang, Long-Sheng; Oblinger, Janet L; Wu, Lai Man Natalie; Miller, Cecelia; Burns, Sarah S
mTOR
神经科学
发表日期：2026
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Single-cell and Spatial Omics Reveals Region-Specific Plasticity and Therapeutic Vulnerabilities in Metastatic High-Risk Neuroblastoma

单细胞和空间组学揭示转移性高危神经母细胞瘤的区域特异性可塑性和治疗脆弱性

期刊:
影响因子:
doi:10.1101/2025.10.19.681936
Wu, Lai Man Natalie; Oblinger, Janet L; Xin, Dazhuan; Rao, Rohit; Zhang, Feng; Adam, Mike; Lopez-Nunez, Oscar; Szabo, Sara; von Allmen, Daniel; Chang, Long-Sheng; Weiss, Brian D; Lu, Q Richard
细胞生物学
单细胞
发表日期：2025
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Anti-tumor effects of the eIF4A inhibitor didesmethylrocaglamide and its derivatives in human and canine osteosarcomas

eIF4A 抑制剂二去甲基罗卡格酰胺及其衍生物对人类和犬骨肉瘤的抗肿瘤作用

期刊:Scientific Reports
影响因子:3.8
doi:10.1038/s41598-024-69171-3
Janet L Oblinger, Jack Wang, Georgia D Wetherell, Garima Agarwal, Tyler A Wilson, Nicole R Benson, Joelle M Fenger, James R Fuchs, A Douglas Kinghorn, Long-Sheng Chang
肿瘤
骨肉瘤
发表日期：2024
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Preclinical evaluation of the third-generation, bi-steric mechanistic target of rapamycin complex 1-selective inhibitor RMC-6272 in NF2-deficient models

雷帕霉素复合物 1-选择性抑制剂 RMC-6272 在 NF2 缺陷模型中的第三代双空间机制靶点的临床前评估

期刊:NeuroOncology Advances
影响因子:3.7
doi:10.1093/noajnl/vdae024
Srirupa Bhattacharyya, Janet L Oblinger, Roberta L Beauchamp, Lili Kosa, Francis Robert, Scott R Plotkin, Long-Sheng Chang, Vijaya Ramesh
信号转导
mTOR
发表日期：2024
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Anti-tumor Effects of the eIF4A Inhibitor Didesmethylrocaglamide and Its Derivatives in Human and Canine Osteosarcomas

eIF4A 抑制剂 Didesmethylrocaglamide 及其衍生物对人类和犬骨肉瘤的抗肿瘤作用

期刊:
影响因子:
doi:10.21203/rs.3.rs-4494024/v1
Janet Oblinger, Jack Wang, Georgia Wetherell, Garima Agarwal, Tyler Wilson, Nicole Benson, Joelle Fenger, James Fuchs, A Douglas Kinghorn, Long Chang
肿瘤
骨肉瘤
发表日期：2024
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Proteasomal pathway inhibition as a potential therapy for NF2-associated meningioma and schwannoma

蛋白酶体通路抑制作为NF2相关脑膜瘤和神经鞘瘤的潜在治疗方法

期刊:Neuro-Oncology
影响因子:13.4
doi:10.1093/neuonc/noad037
Bhattacharyya, Srirupa; Oblinger, Janet L; Beauchamp, Roberta L; Yin, Zhenzhen; Erdin, Serkan; Koundinya, Priya; Ware, Anna D; Ferrer, Marc; Jordan, Justin T; Plotkin, Scott R; Xu, Lei; Chang, Long-Sheng; Ramesh, Vijaya
信号转导
神经科学
发表日期：2023
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Special orthopaedic geriatrics (SOG) - a new multiprofessional care model for elderly patients in elective orthopaedic surgery: a study protocol for a prospective randomized controlled trial of a multimodal intervention in frail patients with hip and knee replacement

特殊骨科老年医学（SOG）——一种针对择期骨科手术老年患者的新型多学科护理模式：一项针对接受髋关节和膝关节置换术的体弱患者的多模式干预前瞻性随机对照试验的研究方案

期刊:BMC Musculoskeletal Disorders
影响因子:2.4
doi:10.1186/s12891-022-05955-w
Kappenschneider, Tobias; Maderbacher, Günther; Weber, Markus; Greimel, Felix; Holzapfel, Dominik; Parik, Lukas; Schwarz, Timo; Leiss, Franziska; Knebl, Michael; Reinhard, Jan; Schraag, Amadeus Dominik; Thieme, Max; Turn, Agathe; Götz, Julia; Zborilova, Magdalena; Pulido, Loreto C; Azar, Fady; Spörrer, Jan-Frederik; Oblinger, Britta; Pfalzgraf, Frederik; Sundmacher, Leonie; Iashchenko, Iryna; Franke, Sebastian; Trabold, Benedikt; Michalk, Katrin; Grifka, Joachim; Meyer, Matthias
发表日期：2022
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Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

神经纤维瘤病：分子发病机制及天然化合物作为潜在治疗方法

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2021.698192
Amaravathi, Anusha; Oblinger, Janet L; Welling, D Bradley; Kinghorn, A Douglas; Chang, Long-Sheng
发表日期：2021
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Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK

布加替尼通过抑制多种酪氨酸激酶（但不抑制 ALK）导致 NF2 缺陷型脑膜瘤和神经鞘瘤的肿瘤缩小

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0252048
Long-Sheng Chang, Janet L Oblinger, Abbi E Smith, Marc Ferrer, Steven P Angus, Eric Hawley, Alejandra M Petrilli, Roberta L Beauchamp, Lars Björn Riecken, Serkan Erdin, Ming Poi, Jie Huang, Waylan K Bessler, Xiaohu Zhang, Rajarshi Guha, Craig Thomas, Sarah S Burns, Thomas S K Gilbert, Li Jiang, Xiao
神经
肿瘤
FER
发表日期：2021
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