Ochsner Scott A相关文献与解析，生知库 | 链接生命科学的每一步

Rojas-Quintero Joselyn, Ochsner Scott A, Lee Hyun-Sung, Cong Christine, Waich Cohen Alan, Colborg Adrianne S, Tsoyi Konstantin, Basil Maria C, Cantu Edward, Rosas Ivan O, McKenna Neil J, San-JosÃ© EstÃ©par RaÃºl, Barjaktarevic Igor, Wilson Andrew A, Polverino Francesca

免疫/内分泌

发表日期：2025

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Lung NR3C1(+) and CXCR6(high) T cells distinguish immunopathogenesis of human emphysema

肺NR3C1(+)和CXCR6(高表达)T细胞可区分人类肺气肿的免疫发病机制

期刊:Communications Biology

影响因子:5.1

doi:10.1038/s42003-025-08698-1

Zhang, Yun; Sauler, Maor; Corry, David B; Ochsner, Scott A; Perusich, Sarah; Song, Li-Zhen; Malo, Joshua; Estepar, Raul San Jose; Polverino, Francesca; Kheradmand, Farrah

Islet single-cell transcriptomic profiling during obesity-induced beta cell expansion in female mice

雌性小鼠肥胖诱导β细胞扩增过程中胰岛单细胞转录组分析

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2025.112031

Masschelin, Peter M; Ochsner, Scott A; Hartig, Sean M; McKenna, Neil J; Cox, Aaron R

Macropinocytosis inhibition attenuates pro-fibrotic responses in lung fibroblasts and pulmonary fibrosis

巨胞饮作用抑制可减弱肺成纤维细胞的促纤维化反应和肺纤维化

期刊:

影响因子:

doi:10.1101/2025.07.09.663937

Rosas, Ivan O; McDowell-Sanchez, Aaron K; Sanchez, Santiago; Cala-Garcia, Juan D; Cohen, Alan R Waich; Echartea, Maria Elisa Ruiz; Ochsner, Scott A; Kraushaar, Daniel; Celada, Lindsay J; Sun, Dandan; Polverino, Francesca; Coarfa, Cristian; McKenna, Neil J; Tsoyi, Konstantin

Single cell transcriptomics in a treatment-segregated cohort exposes a STAT3-regulated therapeutic gap in idiopathic pulmonary fibrosis.

对接受不同治疗的队列进行单细胞转录组学分析，揭示了特发性肺纤维化中 STAT3 调控的治疗缺口

期刊:

影响因子:

doi:10.1101/2025.06.16.659944

McKenna Neil J, Ochsner Scott A, Waich Alan, Cala-Garcia Juan, Echartrea Maria E Ruiz, Grimm Sandra, Poli Fernando, Castillo Rafael Cardenas, Zuluaga Juan D, Poli Sergio, Adams Taylor S, Pineda Ricardo, Moss Benjamin, Ryter Stefan W, Pillich Rudolf T, Villalba Julian A, Kato Kosuke, Hecker Louise, Celada Lindsay J, Sauler Maor, Koenigshoff Melanie, Kaminski Naftali, Raby Benjamin, Agarwal Sandeep, Tsoyi Konstantin, Coarfa Cristian, Rosas Ivan O

Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease

空间转录组学解析慢性阻塞性肺疾病中肺气肿特异性淋巴滤泡B细胞特征

期刊:American Journal of Respiratory and Critical Care Medicine

影响因子:19.4

doi:10.1164/rccm.202303-0507LE

Rojas-Quintero, Joselyn; Ochsner, Scott A; New, Felicia; Divakar, Prajan; Yang, Chen Xi; Wu, Tianshi David; Robinson, Jerid; Chandrashekar, Darshan Shimoga; Banovich, Nicholas E; Rosas, Ivan O; Sauler, Maor; Kheradmand, Farrah; Gaggar, Amit; Margaroli, Camilla; San Jose Estepar, Raul; McKenna, Neil J; Polverino, Francesca

Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress

组蛋白异构体分析揭示了成年小鼠棕色脂肪组织在冷应激反应中的表观遗传变化

期刊:Epigenetics & Chromatin

影响因子:3.5

doi:10.1186/s13072-024-00536-8

Taylor, Bethany C; Steinthal, Loic H; Dias, Michelle; Yalamanchili, Hari Krishna; Ochsner, Scott A; Zapata, Gladys E; Mehta, Nitesh R; McKenna, Neil J; Young, Nicolas L; Nuotio-Antar, Alli M

SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8(+) T cells

SHP2通过抑制CD8(+) T细胞中SKP2靶向的TBET泛素化作用，促进结节病病情加重。

期刊:Science Translational Medicine

影响因子:14.6

doi:10.1126/scitranslmed.ade2581

Celada, Sherly I; Lim, Clarice X; Carisey, Alexandre F; Ochsner, Scott A; Arce Deza, Carlos F; Rexie, Praveen; Poli De Frias, Fernando; Cardenas-Castillo, Rafael; Polverino, Francesca; Hengstschläger, Markus; Tsoyi, Konstantin; McKenna, Neil J; Kheradmand, Farrah; Weichhart, Thomas; Rosas, Ivan O; Van Kaer, Luc; Celada, Lindsay J

Transcriptional regulatory networks of circulating immune cells in type 1 diabetes: A community knowledgebase

型糖尿病循环免疫细胞的转录调控网络：一个社区知识库

期刊:iScience

影响因子:4.1

doi:10.1016/j.isci.2022.104581

Ochsner, Scott A; Pillich, Rudolf T; Rawool, Deepali; Grethe, Jeffrey S; McKenna, Neil J

A human liver chimeric mouse model for non-alcoholic fatty liver disease

用于研究非酒精性脂肪肝疾病的人类肝脏嵌合小鼠模型

期刊:Jhep Reports

影响因子:7.5

doi:10.1016/j.jhepr.2021.100281

Bissig-Choisat, Beatrice; Alves-Bezerra, Michele; Zorman, Barry; Ochsner, Scott A; Barzi, Mercedes; Legras, Xavier; Yang, Diane; Borowiak, Malgorzata; Dean, Adam M; York, Robert B; Galvan, N Thao N; Goss, John; Lagor, William R; Moore, David D; Cohen, David E; McKenna, Neil J; Sumazin, Pavel; Bissig, Karl-Dimiter

Skewed adaptive immune responses are involved in alpha-1 antitrypsin deficiency emphysema.

α1-抗胰蛋白酶缺乏症肺气肿与适应性免疫反应失衡有关

Lung NR3C1(+) and CXCR6(high) T cells distinguish immunopathogenesis of human emphysema

肺NR3C1(+)和CXCR6(高表达)T细胞可区分人类肺气肿的免疫发病机制

Islet single-cell transcriptomic profiling during obesity-induced beta cell expansion in female mice

雌性小鼠肥胖诱导β细胞扩增过程中胰岛单细胞转录组分析

Macropinocytosis inhibition attenuates pro-fibrotic responses in lung fibroblasts and pulmonary fibrosis

巨胞饮作用抑制可减弱肺成纤维细胞的促纤维化反应和肺纤维化

Single cell transcriptomics in a treatment-segregated cohort exposes a STAT3-regulated therapeutic gap in idiopathic pulmonary fibrosis.

对接受不同治疗的队列进行单细胞转录组学分析，揭示了特发性肺纤维化中 STAT3 调控的治疗缺口

Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease

空间转录组学解析慢性阻塞性肺疾病中肺气肿特异性淋巴滤泡B细胞特征

Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress

组蛋白异构体分析揭示了成年小鼠棕色脂肪组织在冷应激反应中的表观遗传变化

SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8(+) T cells

SHP2通过抑制CD8(+) T细胞中SKP2靶向的TBET泛素化作用，促进结节病病情加重。

Transcriptional regulatory networks of circulating immune cells in type 1 diabetes: A community knowledgebase

型糖尿病循环免疫细胞的转录调控网络：一个社区知识库

A human liver chimeric mouse model for non-alcoholic fatty liver disease

用于研究非酒精性脂肪肝疾病的人类肝脏嵌合小鼠模型