Rationale and design of a double-blind randomized non-inferiority clinical trial to evaluate one or two doses of vaccine against human papillomavirus including an epidemiologic survey to estimate vaccine efficacy: The Costa Rica ESCUDDO trial
一项评估单剂或两剂人乳头瘤病毒疫苗疗效的双盲随机非劣效性临床试验的原理和设计,包括一项用于评估疫苗效力的流行病学调查:哥斯达黎加ESCUDDO试验
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doi:10.1016/j.vaccine.2021.11.041
Porras, Carolina; Sampson, Joshua N; Herrero, Rolando; Gail, Mitchell H; Cortés, Bernal; Hildesheim, Allan; Cyr, Jean; Romero, Byron; Schiller, John T; Montero, Christian; Pinto, Ligia A; Schussler, John; Coronado, Karla; Sierra, Mónica S; Kim, Jane J; Torres, Catherine M; Carvajal, Loretto; Wagner, Sarah; Campos, Nicole G; Ocampo, Rebecca; Kemp, Troy J; Zuniga, Michael; Lowy, Douglas R; Avila, Carlos; Chanock, Stephen; Castrillo, Ariane; Estrada, Yenory; Barrientos, Gloriana; Monge, Cindy; Oconitrillo, María Y; Kreimer, Aimée R