Discontinuation versus continuation of hypertonic saline or dornase alfa in modulator treated people with cystic fibrosis (SIMPLIFY): results from two parallel, multicentre, open-label, randomised, controlled, non-inferiority trials
在接受调节剂治疗的囊性纤维化患者中，停用高渗盐水或重组人脱氧核糖核酸酶（dornase alfa）与继续使用高渗盐水或dornase alfa的疗效比较（SIMPLIFY）：两项平行、多中心、开放标签、随机、对照、非劣效性试验的结果
期刊:Lancet Respiratory Medicine
影响因子:32.8
doi:10.1016/S2213-2600(22)00434-9
Mayer-Hamblett, Nicole; Ratjen, Felix; Russell, Renee; Donaldson, Scott H; Riekert, Kristin A; Sawicki, Gregory S; Odem-Davis, Katherine; Young, Julia K; Rosenbluth, Daniel; Taylor-Cousar, Jennifer L; Goss, Christopher H; Retsch-Bogart, George; Clancy, John Paul; Genatossio, Alan; O'Sullivan, Brian P; Berlinski, Ariel; Millard, Susan L; Omlor, Gregory; Wyatt, Colby A; Moffett, Kathryn; Nichols, David P; Gifford, Alex H
