日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Capsid-dependent lentiviral restrictions

衣壳依赖性慢病毒限制

Twentyman, Joy; Emerman, Michael; Ohainle, Molly

A modular CRISPR screen identifies individual and combination pathways contributing to HIV-1 latency

模块化 CRISPR 筛选可识别导致 HIV-1 潜伏的单个和组合通路。

Emily Hsieh ,Derek H Janssens ,Patrick J Paddison ,Edward P Browne ,Steve Henikoff ,Molly OhAinle ,Michael Emerman

A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains

一种可包装病毒的CRISPR系统能够识别多种HIV-1毒株所利用的宿主依赖因子

Vanessa R Montoya ,Trine M Ready ,Abby Felton ,Sydney R Fine ,Molly OhAinle ,Michael Emerman

Patterns of Evolution of TRIM Genes Highlight the Evolutionary Plasticity of Antiviral Effectors in Mammals

TRIM基因的进化模式凸显了哺乳动物抗病毒效应因子的进化可塑性

Fernandes, Alexandre P; OhAinle, Molly; Esteves, Pedro J

Identification of DAXX as a restriction factor of SARS-CoV-2 through a CRISPR/Cas9 screen

通过 CRISPR/Cas9 筛选鉴定 DAXX 为 SARS-CoV-2 的限制因子

Alice Mac Kain # ,Ghizlane Maarifi # ,Sophie-Marie Aicher ,Nathalie Arhel ,Artem Baidaliuk ,Sandie Munier ,Flora Donati ,Thomas Vallet ,Quang Dinh Tran ,Alexandra Hardy ,Maxime Chazal ,Françoise Porrot ,Molly OhAinle ,Jared Carlson-Stevermer ,Jennifer Oki ,Kevin Holden ,Gert Zimmer ,Etienne Simon-Lorière ,Timothée Bruel ,Olivier Schwartz ,Sylvie van der Werf ,Nolwenn Jouvenet ,Sébastien Nisole ,Marco Vignuzzi ,Ferdinand Roesch

TRIM34 restricts HIV-1 and SIV capsids in a TRIM5α-dependent manner

TRIM34 以 TRIM5α 依赖的方式限制 HIV-1 和 SIV 衣壳

Molly Ohainle, Kyusik Kim, Sevnur Komurlu Keceli, Abby Felton, Ed Campbell, Jeremy Luban, Michael Emerman

HIV-CRISPR: A CRISPR/Cas9 Screening Method to Identify Genes Affecting HIV Replication

HIV-CRISPR:一种用于识别影响HIV复制的基因的CRISPR/Cas9筛选方法

Ferdinand Roesch ,Molly OhAinle

Macaque interferon-induced transmembrane proteins limit replication of SHIV strains in an Envelope-dependent manner

猕猴干扰素诱导的跨膜蛋白以包膜依赖的方式限制 SHIV 病毒株的复制

Amit Sharma, Richard N McLaughlin Jr, Ryan S Basom, Caroline Kikawa, Molly OhAinle, Jacob S Yount, Michael Emerman, Julie Overbaugh

A virus-packageable CRISPR screen identifies host factors mediating interferon inhibition of HIV

利用病毒包装的 CRISPR 筛选方法鉴定出介导干扰素抑制 HIV 的宿主因子

Molly OhAinle,Louisa Helms,Jolien Vermeire,Ferdinand Roesch,Daryl Humes,Ryan Basom,Jeffrey J Delrow,Julie Overbaugh,Michael Emerman

A CRISPR screen for factors regulating SAMHD1 degradation identifies IFITMs as potent inhibitors of lentiviral particle delivery

利用 CRISPR 技术筛选调控 SAMHD1 降解的因子,发现 IFITM 是慢病毒颗粒递送的强效抑制剂。

Ferdinand Roesch ,Molly OhAinle ,Michael Emerman