日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessment of HIF2α mutational pathogenicity using microscale thermophoresis

利用微尺度热泳技术评估HIF2α突变致病性

Ferens, Fraser G; Taber, Cassandra C; Eo, Jeffrey J; Ohh, Michael

Erythrocytosis-inducing PHD2 mutations implicate biological role for N-terminal prolyl-hydroxylation in HIF1α oxygen-dependent degradation domain

红细胞增多症诱发的PHD2突变表明N端脯氨酰羟基化在HIF1α氧依赖性降解结构域中发挥生物学作用

Taber, Cassandra C; He, Wenguang; Gasmi-Seabrook, Geneviève M C; Hubert, Mia; Ferens, Fraser G; Ikura, Mitsuhiko; Lee, Jeffrey E; Ohh, Michael

Comparative single-cell transcriptomic profiling of patient-derived renal carcinoma cells in cellular and animal models of kidney cancer.

在肾癌细胞和动物模型中,对患者来源的肾癌细胞进行比较单细胞转录组分析

Huang Richard, Kee Lynn, Gont Alexander, Meens Jalna, Ferens Fraser G, Irwin Meredith S, Ailles Laurie, Yuzwa Scott A, Robinson Claire M, Ohh Michael

Time-resolved NMR detection of prolyl-hydroxylation in intrinsically disordered region of HIF-1α

利用时间分辨核磁共振技术检测HIF-1α固有无序区域中脯氨酰羟基化

He, Wenguang; Gasmi-Seabrook, Geneviève M C; Ikura, Mitsuhiko; Lee, Jeffrey E; Ohh, Michael

Hypoxia and viral infectious diseases

缺氧和病毒感染性疾病

Huang, Richard; Huestis, Melissa; Gan, Esther Shuyi; Ooi, Eng Eong; Ohh, Michael

Hypoxia promotes ligand-independent EGF receptor signaling via hypoxia-inducible factor-mediated upregulation of caveolin-1

缺氧通过缺氧诱导因子介导的caveolin-1上调促进配体非依赖性EGF受体信号传导。

Wang, Yi; Roche, Olga; Xu, Chaoying; Moriyama, Eduardo H; Heir, Pardeep; Chung, Jacky; Roos, Frederik C; Chen, Yonghong; Finak, Greg; Milosevic, Michael; Wilson, Brian C; Teh, Bin Tean; Park, Morag; Irwin, Meredith S; Ohh, Michael

The updated biology of hypoxia-inducible factor

缺氧诱导因子生物学的最新进展

Greer, Samantha N; Metcalf, Julie L; Wang, Yi; Ohh, Michael

Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia

异二聚体VHL-SOCS1 E3泛素连接酶介导的JAK2调控丧失是楚瓦什红细胞增多症的根本原因。

Russell, Ryan C; Sufan, Roxana I; Zhou, Bing; Heir, Pardeep; Bunda, Severa; Sybingco, Stephanie S; Greer, Samantha N; Roche, Olga; Heathcote, Samuel A; Chow, Vinca W K; Boba, Lukasz M; Richmond, Terri D; Hickey, Michele M; Barber, Dwayne L; Cheresh, David A; Simon, M Celeste; Irwin, Meredith S; Kim, William Y; Ohh, Michael

Deregulation of E2-EPF ubiquitin carrier protein in papillary renal cell carcinoma

乳头状肾细胞癌中E2-EPF泛素载体蛋白的失调

Roos, Frederik C; Evans, Andrew J; Brenner, Walburgis; Wondergem, Bill; Klomp, Jeffery; Heir, Pardeep; Roche, Olga; Thomas, Christian; Schimmel, Heiko; Furge, Kyle A; Teh, Bin T; Thüroff, Joachim W; Hampel, Christian; Ohh, Michael

Phospholipase D-mTOR requirement for the Warburg effect in human cancer cells

磷脂酶D-mTOR在人类癌细胞中对Warburg效应的需求

Toschi, Alfredo; Lee, Evan; Thompson, Sebastian; Gadir, Noga; Yellen, Paige; Drain, C Michael; Ohh, Michael; Foster, David A