日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Monomeric annexin A2 is an oxygen-regulated toll-like receptor 2 ligand and adjuvant

单体膜联蛋白A2是一种氧调节的Toll样受体2配体和佐剂

Andersen, Brian M; Xia, Junzhe; Epstein, Alan L; Ohlfest, John R; Chen, Wei; Blazar, Bruce R; Pennell, Christopher A; Olin, Michael R

Vaccination with dendritic cells loaded with allogeneic brain tumor cells for recurrent malignant brain tumors induces a CD4(+)IL17(+) response

用负载同种异体脑肿瘤细胞的树突状细胞进行疫苗接种,可诱导复发性恶性脑肿瘤产生 CD4(+)IL17(+) 反应。

Olin, Michael R; Low, Walter; McKenna, David H; Haines, Stephen J; Dahlheimer, Tambra; Nascene, David; Gustafson, Michael P; Dietz, Allan B; Clark, H Brent; Chen, Wei; Blazar, Bruce; Ohlfest, John R; Moertel, Christopher

Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8+ T-cell responses

微环DNA在诱导抗原特异性CD8+ T细胞反应方面优于质粒DNA。

Dietz, Wynette M; Skinner, Nicole E B; Hamilton, Sara E; Jund, Michelle D; Heitfeld, Suzanne M; Litterman, Adam J; Hwu, Patrick; Chen, Zhi-Ying; Salazar, Andres M; Ohlfest, John R; Blazar, Bruce R; Pennell, Christopher A; Osborn, Mark J

Immunologic privilege in the central nervous system and the blood-brain barrier

中枢神经系统和血脑屏障的免疫豁免

Muldoon, Leslie L; Alvarez, Jorge I; Begley, David J; Boado, Ruben J; Del Zoppo, Gregory J; Doolittle, Nancy D; Engelhardt, Britta; Hallenbeck, John M; Lonser, Russell R; Ohlfest, John R; Prat, Alexandre; Scarpa, Maurizio; Smeyne, Richard J; Drewes, Lester R; Neuwelt, Edward A

Function of the blood-brain barrier and restriction of drug delivery to invasive glioma cells: findings in an orthotopic rat xenograft model of glioma

血脑屏障的功能及药物向侵袭性胶质瘤细胞递送的限制:胶质瘤原位大鼠异种移植模型的研究结果

Agarwal, Sagar; Manchanda, Pooja; Vogelbaum, Michael A; Ohlfest, John R; Elmquist, William F

Profound impairment of adaptive immune responses by alkylating chemotherapy.

烷化化疗药物可严重损害适应性免疫反应

Litterman Adam J, Zellmer David M, Grinnen Karen L, Hunt Matthew A, Dudek Arkadiusz Z, Salazar Andres M, Ohlfest John R

Vaccine injection site matters: qualitative and quantitative defects in CD8 T cells primed as a function of proximity to the tumor in a murine glioma model.

疫苗注射部位很重要:在小鼠神经胶质瘤模型中,CD8 T 细胞的定性和定量缺陷与肿瘤的接近程度有关

Ohlfest John R, Andersen Brian M, Litterman Adam J, Xia Junzhe, Pennell Christopher A, Swier Lauryn E, Salazar Andres M, Olin Michael R

Immunogenicity of murine solid tumor models as a defining feature of in vivo behavior and response to immunotherapy

小鼠实体瘤模型的免疫原性是体内行为和免疫治疗反应的决定性特征

Lechner, Melissa G; Karimi, Saman S; Barry-Holson, Keegan; Angell, Trevor E; Murphy, Katherine A; Church, Connor H; Ohlfest, John R; Hu, Peisheng; Epstein, Alan L

Increasing the efficacy of tumor cell vaccines by enhancing cross priming

通过增强交叉启动来提高肿瘤细胞疫苗的疗效

Andersen, Brian M; Ohlfest, John R

Active efflux of Dasatinib from the brain limits efficacy against murine glioblastoma: broad implications for the clinical use of molecularly targeted agents

达沙替尼从脑内主动外排限制了其对小鼠胶质母细胞瘤的疗效:对分子靶向药物的临床应用具有广泛意义

Agarwal, Sagar; Mittapalli, Rajendar K; Zellmer, David M; Gallardo, Jose L; Donelson, Randy; Seiler, Charlie; Decker, Stacy A; Santacruz, Karen S; Pokorny, Jenny L; Sarkaria, Jann N; Elmquist, William F; Ohlfest, John R