ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression
ALS 单核细胞衍生的小胶质细胞样细胞显示与疾病进展相关的细胞质 TDP-43 积累、DNA 损伤和细胞特异性吞噬功能受损
期刊:Journal of Neuroinflammation
影响因子:9.3
doi:10.1186/s12974-022-02421-1
Hazel Quek, Carla Cuní-López, Romal Stewart, Tiziana Colletti, Antonietta Notaro, Tam Hong Nguyen, Yifan Sun, Christine C Guo, Michelle K Lupton, Tara L Roberts, Yi Chieh Lim, Lotta E Oikari, Vincenzo La Bella, Anthony R White