日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

MSI2 is required for maintaining activated myelodysplastic syndrome stem cells

MSI2是维持活化的骨髓增生异常综合征干细胞所必需的。

Taggart, James; Ho, Tzu-Chieh; Amin, Elianna; Xu, Haiming; Barlowe, Trevor S; Perez, Alexendar R; Durham, Benjamin H; Tivnan, Patrick; Okabe, Rachel; Chow, Arthur; Vu, Ly; Park, Sun Mi; Prieto, Camila; Famulare, Christopher; Patel, Minal; Lengner, Christopher J; Verma, Amit; Roboz, Gail; Guzman, Monica; Klimek, Virginia M; Abdel-Wahab, Omar; Leslie, Christina; Nimer, Stephen D; Kharas, Michael G

Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia

Musashi-2 调节正常造血过程并促进侵袭性髓系白血病。

Kharas, Michael G; Lengner, Christopher J; Al-Shahrour, Fatima; Bullinger, Lars; Ball, Brian; Zaidi, Samir; Morgan, Kelly; Tam, Winnie; Paktinat, Mahnaz; Okabe, Rachel; Gozo, Maricel; Einhorn, William; Lane, Steven W; Scholl, Claudia; Fröhling, Stefan; Fleming, Mark; Ebert, Benjamin L; Gilliland, D Gary; Jaenisch, Rudolf; Daley, George Q

Hedgehog signaling is dispensable for adult murine hematopoietic stem cell function and hematopoiesis

Hedgehog信号通路对于成年小鼠造血干细胞功能和造血作用并非必需。

Hofmann, Inga; Stover, Elizabeth H; Cullen, Dana E; Mao, Junhao; Morgan, Kelly J; Lee, Benjamin H; Kharas, Michael G; Miller, Peter G; Cornejo, Melanie G; Okabe, Rachel; Armstrong, Scott A; Ghilardi, Nico; Gould, Stephen; de Sauvage, Frederic J; McMahon, Andrew P; Gilliland, D Gary

The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo

小分子酪氨酸激酶抑制剂AMN107在体外和体内均能抑制TEL-PDGFRβ和FIP1L1-PDGFRα。

Stover, Elizabeth H; Chen, Jing; Lee, Benjamin H; Cools, Jan; McDowell, Elizabeth; Adelsperger, Jennifer; Cullen, Dana; Coburn, Allison; Moore, Sandra A; Okabe, Rachel; Fabbro, Doriano; Manley, Paul W; Griffin, James D; Gilliland, D Gary

Early placental insulin-like protein (INSL4 or EPIL) in placental and fetal membrane growth

胎盘和胎膜生长中的早期胎盘胰岛素样蛋白(INSL4 或 EPIL)

Millar, Lynnae; Streiner, Nicole; Webster, Lisa; Yamamoto, Sandra; Okabe, Rachel; Kawamata, Tasha; Shimoda, Jacqueline; Büllesbach, Erika; Schwabe, Christian; Bryant-Greenwood, Gillian

PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder.

PKC412 抑制锌指 198-成纤维细胞生长因子受体 1 融合酪氨酸激酶,可用于治疗干细胞骨髓增生性疾病

Chen Jing, Deangelo Daniel J, Kutok Jeffery L, Williams Ifor R, Lee Benjamin H, Wadleigh Martha, Duclos Nicole, Cohen Sarah, Adelsperger Jennifer, Okabe Rachel, Coburn Allison, Galinsky Ilene, Huntly Brian, Cohen Pamela S, Meyer Thomas, Fabbro Doriano, Roesel Johannes, Banerji Lolita, Griffin James D, Xiao Sheng, Fletcher Jonathan A, Stone Richard M, Gilliland D Gary