Okochi Masayasu相关文献与解析，生知库 | 链接生命科学的每一步

Breimann Stephan, Kamp Frits, Basset Gabriele, Abou-Ajram Claudia, GÃ¼ner GÃ¶khan, Yanagida Kanta, Okochi Masayasu, MÃ¼ller Stephan A, Lichtenthaler Stefan F, Langosch Dieter, Frishman Dmitrij, Steiner Harald

人工智能

发表日期：2025

文献求助收藏

Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the Î³-secretase subunit presenilin.

不同的跨膜结构域决定了α-分泌酶亚基早老素的切割活性的特异性和效率

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1016/j.jbc.2023.104626

Schmidt Fabian C, Fitz Katja, Feilen Lukas P, Okochi Masayasu, Steiner Harald, Langosch Dieter

免疫/内分泌

发表日期：2023

文献求助收藏

Switched Aβ43 generation in familial Alzheimer's disease with presenilin 1 mutation

家族性阿尔茨海默病伴早老素1突变中Aβ43的生成发生转换

期刊:Translational Psychiatry

影响因子:6.2

doi:10.1038/s41398-021-01684-1

Kakuda, Nobuto; Takami, Mako; Okochi, Masayasu; Kasuga, Kensaku; Ihara, Yasuo; Ikeuchi, Takeshi

阿尔茨海默症

发表日期：2021

文献求助收藏

Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase

最终筛选：γ-分泌酶生成致病性β-淀粉样蛋白肽

期刊:Cell Stress

影响因子:3

doi:10.15698/cst2018.11.162

Steiner, Harald; Fukumori, Akio; Tagami, Shinji; Okochi, Masayasu

发表日期：2018

文献求助收藏

Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-Î² accumulation modifier.

对不同小鼠品系的转录组分析表明，驱动蛋白轻链-1剪接是淀粉样蛋白-β积累的调节因子

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.1307345111

Morihara Takashi, Hayashi Noriyuki, Yokokoji Mikiko, Akatsu Hiroyasu, Silverman Michael A, Kimura Nobuyuki, Sato Masahiro, Saito Yuhki, Suzuki Toshiharu, Yanagida Kanta, Kodama Takashi S, Tanaka Toshihisa, Okochi Masayasu, Tagami Shinji, Kazui Hiroaki, Kudo Takashi, Hashimoto Ryota, Itoh Naohiro, Nishitomi Kouhei, Yamaguchi-Kabata Yumi, Tsunoda Tatsuhiko, Takamura Hironori, Katayama Taiichi, Kimura Ryo, Kamino Kouzin, Hashizume Yoshio, Takeda Masatoshi

Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex.

人类 CRB2 通过与早老素复合物结合来抑制 γ-分泌酶对淀粉样前体蛋白的切割

期刊:Journal of Biological Chemistry

影响因子:3.9

doi:10.1074/jbc.M109.038760

Mitsuishi Yachiyo, Hasegawa Hiroshi, Matsuo Akinori, Araki Wataru, Suzuki Toshiharu, Tagami Shinji, Okochi Masayasu, Takeda Masatoshi, Roepman Ronald, Nishimura Masaki

Laughter and humor as complementary and alternative medicines for dementia patients

笑声和幽默作为痴呆症患者的辅助和替代疗法

期刊:BMC Complementary and Alternative Medicine

影响因子:3.4

doi:10.1186/1472-6882-10-28

Takeda, Masatoshi; Hashimoto, Ryota; Kudo, Takashi; Okochi, Masayasu; Tagami, Shinji; Morihara, Takashi; Sadick, Golam; Tanaka, Toshihisa

发表日期：2010

文献求助收藏

The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system

由APLP1衍生的Aβ样肽的28个氨基酸形式是中枢神经系统中Aβ42产生的替代标志物。

期刊:EMBO Molecular Medicine

影响因子:8.3

doi:10.1002/emmm.200900026

Yanagida, Kanta; Okochi, Masayasu; Tagami, Shinji; Nakayama, Taisuke; Kodama, Takashi S; Nishitomi, Kouhei; Jiang, Jingwei; Mori, Kohji; Tatsumi, Shin-Ichi; Arai, Tetsuaki; Ikeuchi, Takeshi; Kasuga, Kensaku; Tokuda, Takahiko; Kondo, Masaki; Ikeda, Masaki; Deguchi, Kentaro; Kazui, Hiroaki; Tanaka, Toshihisa; Morihara, Takashi; Hashimoto, Ryota; Kudo, Takashi; Steiner, Harald; Haass, Christian; Tsuchiya, Kuniaki; Akiyama, Haruhiko; Kuwano, Ryozo; Takeda, Masatoshi

Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation

信号肽肽酶介导的膜内加工调控丙型肝炎病毒核心蛋白的膜定位和病毒增殖。

期刊:Journal of Virology

影响因子:3.8

doi:10.1128/JVI.00306-08

Okamoto, Kiyoko; Mori, Yoshio; Komoda, Yasumasa; Okamoto, Toru; Okochi, Masayasu; Takeda, Masatoshi; Suzuki, Tetsuro; Moriishi, Kohji; Matsuura, Yoshiharu

Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1

Notch信号通路的调控是通过Notch-1 S3切割精度的动态变化实现的。

期刊:Molecular and Cellular Biology

影响因子:2.7

doi:10.1128/MCB.00863-07

Tagami, Shinji; Okochi, Masayasu; Yanagida, Kanta; Ikuta, Akiko; Fukumori, Akio; Matsumoto, Naohiko; Ishizuka-Katsura, Yoshiko; Nakayama, Taisuke; Itoh, Naohiro; Jiang, Jingwei; Nishitomi, Kouhei; Kamino, Kouzin; Morihara, Takashi; Hashimoto, Ryota; Tanaka, Toshihisa; Kudo, Takashi; Chiba, Shigeru; Takeda, Masatoshi

Charting Î³-secretase substrates by explainable AI.

利用可解释人工智能绘制 α-分泌酶底物图

Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the Î³-secretase subunit presenilin.

不同的跨膜结构域决定了α-分泌酶亚基早老素的切割活性的特异性和效率

Switched Aβ43 generation in familial Alzheimer's disease with presenilin 1 mutation

家族性阿尔茨海默病伴早老素1突变中Aβ43的生成发生转换

Making the final cut: pathogenic amyloid-β peptide generation by γ-secretase

最终筛选：γ-分泌酶生成致病性β-淀粉样蛋白肽

Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-Î² accumulation modifier.

对不同小鼠品系的转录组分析表明，驱动蛋白轻链-1剪接是淀粉样蛋白-β积累的调节因子

Human CRB2 inhibits gamma-secretase cleavage of amyloid precursor protein by binding to the presenilin complex.

人类 CRB2 通过与早老素复合物结合来抑制 γ-分泌酶对淀粉样前体蛋白的切割

Laughter and humor as complementary and alternative medicines for dementia patients

笑声和幽默作为痴呆症患者的辅助和替代疗法

The 28-amino acid form of an APLP1-derived Abeta-like peptide is a surrogate marker for Abeta42 production in the central nervous system

由APLP1衍生的Aβ样肽的28个氨基酸形式是中枢神经系统中Aβ42产生的替代标志物。

Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation

信号肽肽酶介导的膜内加工调控丙型肝炎病毒核心蛋白的膜定位和病毒增殖。

Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1

Notch信号通路的调控是通过Notch-1 S3切割精度的动态变化实现的。