日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Lebrikizumab Rapidly Lowers Inflammatory Biomarkers with Clinical Correlations in Moderate-to-Severe Atopic Dermatitis

Lebrikizumab 可快速降低中重度特应性皮炎患者的炎症生物标志物,且与临床表现相关

Guttman-Yassky, Emma; Sun, Zhe; Mena, Laura Rebeca; Hahn, Nathan; Nickoloff, Brian J; Preuss, Christoph; Siu, Kimberly; Natalie, Chitra R; Gallo, Gaia; Wolf, Eric; Eyerich, Kilian; Aparici, Mònica; Benschop, Robert J; Okragly, Angela

Lebrikizumab decreases type 2 inflammatory biomarker levels in patients with asthma: data from randomized phase 3 trials (LAVOLTA I and II)

Lebrikizumab 可降低哮喘患者的 2 型炎症生物标志物水平:来自随机 3 期试验(LAVOLTA I 和 II)的数据

Szefler, Stanley; Corren, Jonathan; Silverberg, Jonathan I; Okragly, Angela; Sun, Zhe; Natalie, Chitra R; Zitnik, Ralph; Siu, Kimberly; Blauvelt, Andrew

The blood proteomic signature of prurigo nodularis reveals distinct inflammatory and neuropathic endotypes: A cluster analysis

结节性痒疹的血液蛋白质组学特征揭示了不同的炎症性和神经性内型:聚类分析

Parthasarathy, Varsha; Cravero, Karen; Xu, Lillian; Deng, Junwen; Sun, Zhe; Engle, Sarah M; Sims, Jonathan T; Okragly, Angela J; Kwatra, Shawn G

Serum Interleukin-13 and Caspase 8 are Elevated in Prurigo Nodularis

结节性痒疹患者血清白细胞介素-13和半胱天冬酶8水平升高

Ju, Teresa; Labib, Angelina; Nattkemper, Leigh; Engle, Sarah; Auxier, Autum; Hahn, Nathan; Sissons, Sean; Sims, Jonathan T; Sun, Zhe; Okragly, Angela J; Yosipovitch, Gil

Binding, Neutralization and Internalization of the Interleukin-13 Antibody, Lebrikizumab

白细胞介素-13 抗体 Lebrikizumab 的结合、中和和内化

Angela J Okragly, Aya Ryuzoji, Isabella Wulur, Montanea Daniels, Robert D Van Horn, Chetan N Patel, Robert J Benschop

Circulating plasma IL-13 and periostin are dysregulated type 2 inflammatory biomarkers in prurigo nodularis: A cluster analysis

循环血浆IL-13和骨膜蛋白是结节性痒疹中失调的2型炎症生物标志物:聚类分析

Parthasarathy, Varsha; Cravero, Karen; Deng, Junwen; Sun, Zhe; Engle, Sarah M; Auxier, Autum N; Hahn, Nathan; Sims, Jonathan T; Okragly, Angela J; Alphonse, Martin P; Kwatra, Shawn G

Generation and Characterization of Torudokimab (LY3375880): A Monoclonal Antibody That Neutralizes Interleukin-33

Torudokimab (LY3375880) 的生成和表征:一种中和白细胞介素 33 的单克隆抗体

Angela J Okragly, Katie Brannon Corwin, Marikka Elia, Dongmei He, Oliver Schroeder, Qing Zhang, Tatiyana Shiyanova, Stuart Bright, Sarah B Dicker, Lukasz Chlewicki, Stephanie M E Truhlar, Julian Davies, Chetan N Patel, Robert J Benschop

Interleukin-33 Contributes Toward Loss of Tolerance by Promoting B-Cell-Activating Factor of the Tumor-Necrosis-Factor Family (BAFF)-Dependent Autoantibody Production

白细胞介素 33 通过促进肿瘤坏死因子家族 (BAFF) 依赖的 B 细胞活化因子导致耐受性丧失

William A Rose 2nd, Angela J Okragly, Ningjie N Hu, Montanea R Daniels, Andrea P Martin, Yi Ting Koh, Kristine Kikly, Robert J Benschop

IL-33 released by alum is responsible for early cytokine production and has adjuvant properties

明矾释放的IL-33负责早期细胞因子的产生,并具有佐剂特性。

Rose, William A 2nd; Okragly, Angela J; Patel, Chetan N; Benschop, Robert J