日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

STAT3-Dependent Regulation of CFTR and Ciliogenesis Is Essential for Mucociliary Clearance and Innate Airway Defense in Hyper-IgE Syndrome

STAT3依赖的CFTR和纤毛发生调控对于高IgE综合征中的黏液纤毛清除和先天性气道防御至关重要

Sun, Ling; Walls, Samantha A; Dang, Hong; Quinney, Nancy L; Sears, Patrick R; Sadritabrizi, Taraneh; Hasegawa, Koichi; Okuda, Kenichi; Asakura, Takanori; Chang, Xiuya; Zheng, Meiqi; Mikami, Yu; Dizmond, Felicia U; Danilova, Daniela; Zhou, Lynn; Deshmukh, Anshulika; Cholon, Deborah M; Radicioni, Giorgia; Rogers, Troy D; Kissner, William J; Markovetz, Matthew R; Guhr Lee, Tara N; Gutay, Mark I; Esther, Charles R Jr; Chua, Michael; Grubb, Barbara R; Ehre, Camille; Kesimer, Mehmet; Hill, David B; Ostrowski, Lawrence E; Button, Brian; Gentzsch, Martina; Robinson, Chevalia; Olivier, Kenneth N; Freeman, Alexandra F; Randell, Scott H; Vladar, Eszter; O'Neal, Wanda K; Boucher, Richard C; Chen, Gang

Airway Epithelial Heterogeneity and Mucus Plugging in Asthmatic Bronchioles

哮喘细支气管气道上皮异质性和黏液栓塞

Schworer, Stephen A; Murano, Hiroaki; Dang, Hong; Markovetz, Matthew R; Saito, Minako; Kato, Takafumi; Asakura, Takanori; Chen, Gang; Gilmore, Rodney C; Morton, Lisa C; van Heusden, Catharina; Chua, Michael; Strickler, Ella; Wisniewski, Zoey Y; Crisp, Gillian; Mitchell, Elodie; Doherty, Kayleigh A; Mastan, Shania; Trejo Bittar, Humberto E; Cody, Brittany A; Trudeau, John B; De la Cruz, Gabriela; Ralph, Lauren M; Askin, Frederic B; Panettieri, Reynold A Jr; Koziol-White, Cynthia J; Byrd, Kevin M; Livraghi-Butrico, Alessandra; O'Neal, Wanda K; Randell, Scott H; Wenzel, Sally E; Okuda, Kenichi; Boucher, Richard C Jr

Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.

长期气道外植体培养能够研究健康、疾病和病毒发病机制

Lee-Ferris Rhianna E, Okuda Kenichi, Galiger Jacob R, Schworer Stephen A, Rogers Troy D, Dang Hong, Gilmore Rodney, Edwards Caitlin, Crisp Gillian, Nakano Satoko, Cawley Anne M, Pickles Raymond J, Gallant Samuel C, Crisci Elisa, Rivier Lauraine, Hagood James S, O'Neal Wanda K, Baric Ralph S, Grubb Barbara R, Boucher Richard C, Randell Scott H

Preferential apical infection and spread of human metapneumovirus highlights the importance of inhaled delivery of neutralizing monoclonal antibody to treat established infections

人偏肺病毒优先发生于肺尖感染和扩散,凸显了吸入中和单克隆抗体治疗已确诊感染的重要性。

Tiruthani, Karthik; Card, Madison P; Wolf, Whitney; Shen, Limei; Schaefer, Alison; Fritz, Marshall; Okuda, Kenichi; Harkema, Jack R; Mousa, Jarrod J; J Pickles, Raymond; Lai, Samuel K

Dysregulation of lung epithelial cell homeostasis and immunity contributes to Middle East respiratory syndrome coronavirus disease severity

肺上皮细胞稳态和免疫失调是导致中东呼吸综合征冠状病毒疾病严重程度增加的原因之一。

Sims, Amy C; Schäfer, Alexandra; Okuda, Kenichi; Leist, Sarah R; Kocher, Jacob F; Cockrell, Adam S; Hawkins, Padraig E; Furusho, Minako; Jensen, Kara L; Kyle, Jennifer E; Burnum-Johnson, Kristin E; Stratton, Kelly G; Lamar, Natalie C; Niccora, Carrie D; Weitz, Karl K; Smith, Richard D; Metz, Thomas O; Waters, Katrina M; Boucher, Richard C; Montgomery, Stephanie A; Baric, Ralph S; Sheahan, Timothy P

Airway epithelial SARS-CoV-2 infectious and repair responses: relationships to age, sex, and post-COVID pulmonary syndromes

气道上皮细胞对SARS-CoV-2的感染和修复反应:与年龄、性别和COVID-19后肺部综合征的关系

Dang, Hong; Edwards, Caitlin E; Kato, Takafumi; Reidel, Boris; Meganck, Rita M; Esther, Charles R Jr; Ehre, Camille; Fulcher, M Leslie; Bailey, Alexis B; Cooley, Michelle R; Mikami, Yu; Asakura, Takanori; Hawkins, Padraig E; Furusho, Minako; Myers, Jeffrey L; Konopka, Kristine; Gerayeli, Firoozeh V; Park, Hye Yun; Sin, Don D; Livraghi-Butrico, Alessandra; Okuda, Kenichi; Pickles, Raymond J; Klein, Sabra; Randell, Scott H; O'Neal, Wanda K; Baric, Ralph S; Boucher, Richard C

Pulmonary Ionocytes: What Are They Transporting and Which Way?

肺离子细胞:它们运输什么物质?运输方向是什么?

Okuda, Kenichi; Gentzsch, Martina

Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis

近端和远端细支气管在非囊性纤维化支气管扩张的发病机制中发挥作用

Asakura, Takanori; Okuda, Kenichi; Chen, Gang; Dang, Hong; Kato, Takafumi; Mikami, Yu; Schworer, Stephen A; Gilmore, Rodney C; Radicioni, Giorgia; Hawkins, Padraig; Barbosa Cardenas, Selene Margarita; Saito, Minako; Cawley, Anne Marie; De la Cruz, Gabriela; Chua, Michael; Alexis, Neil E; Masugi, Yohei; Noone, Peadar G; Ribeiro, Carla M P; Kesimer, Mehmet; Olivier, Kenneth N; Hasegawa, Naoki; Randell, Scott H; O'Neal, Wanda K; Boucher, Richard C

SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia.

SARS-CoV-2 变异株在原代人呼吸道上皮细胞中的适应性和适应性值得关注

Meganck Rita M, Edwards Caitlin E, Mallory Michael L, Lee Rhianna E, Dang Hong, Bailey Alexis B, Wykoff Jason A, Gallant Samuel C, Zhu Deanna R, Yount Boyd L, Kato Takafumi, Shaffer Kendall M, Nakano Satoko, Cawley Anne Marie, Sontake Vishwaraj, Wang Jeremy R, Hagan Robert S, Miller Melissa B, Tata Purushothama Rao, Randell Scott H, Tse Longping V, Ehre Camille, Okuda Kenichi, Boucher Richard C, Baric Ralph S

Associations of COVID-19 symptoms with omicron subvariants BA.2 and BA.5, host status, and clinical outcomes in Japan: a registry-based observational study

日本COVID-19症状与omicron亚型BA.2和BA.5、宿主状态及临床结局的关联:一项基于登记数据的观察性研究

Nakakubo, Sho; Kishida, Naoki; Okuda, Kenichi; Kamada, Keisuke; Iwama, Masami; Suzuki, Masaru; Yokota, Isao; Ito, Yoichi M; Nasuhara, Yasuyuki; Boucher, Richard C; Konno, Satoshi