日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Preclinical and clinical characterization of the RORγt inhibitor JNJ-61803534

RORγt抑制剂JNJ-61803534的临床前和临床表征

Xiaohua Xue, Aimee De Leon-Tabaldo, Rosa Luna-Roman, Glenda Castro, Michael Albers, Freddy Schoetens, Samuel DePrimo, Damayanthi Devineni, Thomas Wilde, Steve Goldberg, Olaf Kinzel, Thomas Hoffmann, Anne M Fourie, Robin L Thurmond

The nuclear bile acid receptor FXR controls the liver derived tumor suppressor histidine-rich glycoprotein

核胆汁酸受体 FXR 控制肝源性肿瘤抑制因子富含组氨酸的糖蛋白

Ulrich Deuschle, Manfred Birkel, Eva Hambruch, Martin Hornberger, Olaf Kinzel, Sanja Perović-Ottstadt, Andreas Schulz, Ulrike Hahn, Michael Burnet, Claus Kremoser

FXR controls the tumor suppressor NDRG2 and FXR agonists reduce liver tumor growth and metastasis in an orthotopic mouse xenograft model

FXR 控制肿瘤抑制因子 NDRG2,FXR 激动剂减少小鼠原位异种移植模型中的肝肿瘤生长和转移

Ulrich Deuschle, Julia Schüler, Andreas Schulz, Thomas Schlüter, Olaf Kinzel, Ulrich Abel, Claus Kremoser