Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.
脐带因子和肽聚糖通过 mincle/CARD9 信号传导和炎症小体重现了分枝杆菌的 Th17 促进佐剂活性
期刊:Journal of Immunology
影响因子:3.4
doi:10.4049/jimmunol.1203343
Shenderov Kevin, Barber Daniel L, Mayer-Barber Katrin D, Gurcha Sudagar S, Jankovic Dragana, Feng Carl G, Oland Sandy, Hieny Sara, Caspar Pat, Yamasaki Sho, Lin Xin, Ting Jenny P-Y, Trinchieri Giorgio, Besra Gurdyal S, Cerundolo Vincenzo, Sher Alan
