Ole Helm相关文献与解析，生知库 | 链接生命科学的每一步

Antonin Gellrich, Franka Scharfenberg, Florian Peters, Martin Sammel, Ole Helm, Fred Armbrust, Frederike Schmidt, Juliane Lokau, Christoph Garbers, Susanne Sebens, Philipp Arnold, Christoph Becker-Pauly

肿瘤

发表日期：2021

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Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses

壳聚糖纳米颗粒作为抗原载体诱导有效的肿瘤特异性T细胞反应

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0239369

Frederik Walter ，Elsa Winter ，Sascha Rahn ，Judith Heidland ，Saskia Meier ，Anna-Maria Struzek ，Marcus Lettau ，Lisa-Marie Philipp ，Silje Beckinger ，Lilli Otto ，Julia Luisa Möller ，Ole Helm ，Daniela Wesch ，Regina Scherließ ，Susanne Sebens

Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells

炎症相关的胰腺肿瘤发生：琥珀酸脱氢酶（亚基 B）的上调会降低胰腺导管上皮细胞的细胞生长

期刊:Cancers

影响因子:

doi:10.3390/cancers12010042

Sascha Rahn, Philippe Dänzer Barbosa, Julia Luisa Möller, Nourhane Ammar, Tobias Demetrowitsch, Ole Helm, Daniela Wesch, Bence Sipos, Christoph Röcken, Karin Schwarz, Heiner Schäfer, Susanne Sebens

The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection

肝脏微环境和 TRAIL-R2 对胰腺癌术后肝转移灶生长的影响

期刊:Cancers

影响因子:

doi:10.3390/cancers11060745

Lauritz Miarka, Charlotte Hauser, Ole Helm, Dörthe Holdhof, Silje Beckinger, Jan-Hendrik Egberts, Jan-Paul Gundlach, Lennart Lenk, Sascha Rahn, Wolfgang Mikulits, Anna Trauzold, Susanne Sebens

POLE Score: a comprehensive profiling of programmed death 1 ligand 1 expression in pancreatic ductal adenocarcinoma

POLE 评分：胰腺导管腺癌中程序性死亡 1 配体 1 表达的综合分析

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.26705

Sascha Rahn, Sandra Krüger, Ruben Mennrich, Lisa Goebel, Daniela Wesch, Hans-Heinrich Oberg, Ilka Vogel, Michael Ebsen, Christoph Röcken, Ole Helm, Susanne Sebens

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

糖尿病是胰腺癌的危险因素：高血糖促进胰腺导管上皮细胞的上皮-间质转化和干细胞特性

期刊:Cancer Letters

影响因子:9.1

doi:10.1016/j.canlet.2017.12.004

Sascha Rahn, Vivien Zimmermann, Fabrice Viol, Hendrike Knaack, Kerstin Stemmer, Lena Peters, Lennart Lenk, Hendrik Ungefroren, Dieter Saur, Heiner Schäfer, Ole Helm, Susanne Sebens

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma

肝脏微环境从根本上决定了胰腺导管腺癌的肿瘤细胞休眠和转移生长

期刊:Oncoimmunology

影响因子:

doi:10.1080/2162402X.2017.1368603

Lennart Lenk, Maren Pein, Olga Will, Beatriz Gomez, Fabrice Viol, Charlotte Hauser, Jan-Hendrik Egberts, Jan-Paul Gundlach, Ole Helm, Sanjay Tiwari, Ralf Weiskirchen, Stefan Rose-John, Christoph Röcken, Wolfgang Mikulits, Patrick Wenzel, Günter Schneider, Dieter Saur, Heiner Schäfer, Susanne Sebens

Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro

典型裂解位点的癌症相关突变不会影响金属蛋白酶 meprin β 释放 CD99，但会改变体外细胞迁移

期刊:Oncotarget

影响因子:

doi:10.18632/oncotarget.18966

Tillmann Bedau, Neele Schumacher, Florian Peters, Johannes Prox, Philipp Arnold, Tomas Koudelka, Ole Helm, Frederike Schmidt, Björn Rabe, Marlene Jentzsch, Philip Rosenstiel, Susanne Sebens, Andreas Tholey, Stefan Rose-John, Christoph Becker-Pauly

Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1

胰腺肿瘤细胞中转化生长因子 β1 对 TRAIL-R1 信号传导的负向控制涉及 Smad 依赖性的 TRAIL-R1 下调

期刊:Cellular Signalling

影响因子:4.4

doi:10.1016/j.cellsig.2016.07.016

David I Radke, Hendrik Ungefroren, Ole Helm, Susann Voigt, Gökhan Alp, Hendrik Braun, Sebastian Hübner, Janine Dilchert, Susanne Sebens, Dieter Adam, Holger Kalthoff, Anna Trauzold

The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1

抗氧化转录因子核因子 E2 相关因子-2 (Nrf2) 抵消 TGF-β1 介导的胰腺导管上皮细胞生长抑制 -Nrf2 作为 TGF-β1 促肿瘤发生功能的决定因素

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-016-2191-7

Geeske Genrich, Marcus Kruppa, Lennart Lenk, Ole Helm, Anna Broich, Sandra Freitag-Wolf, Christoph Röcken, Bence Sipos, Heiner Schäfer, Susanne Sebens

Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R

癌症相关 Meprin Βeta 变体 G45R 和 G89R 的表征

Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses

壳聚糖纳米颗粒作为抗原载体诱导有效的肿瘤特异性T细胞反应

Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells

炎症相关的胰腺肿瘤发生：琥珀酸脱氢酶（亚基 B）的上调会降低胰腺导管上皮细胞的细胞生长

The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection

肝脏微环境和 TRAIL-R2 对胰腺癌术后肝转移灶生长的影响

POLE Score: a comprehensive profiling of programmed death 1 ligand 1 expression in pancreatic ductal adenocarcinoma

POLE 评分：胰腺导管腺癌中程序性死亡 1 配体 1 表达的综合分析

Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells

糖尿病是胰腺癌的危险因素：高血糖促进胰腺导管上皮细胞的上皮-间质转化和干细胞特性

The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma

肝脏微环境从根本上决定了胰腺导管腺癌的肿瘤细胞休眠和转移生长

Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro

典型裂解位点的癌症相关突变不会影响金属蛋白酶 meprin β 释放 CD99，但会改变体外细胞迁移

Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1

胰腺肿瘤细胞中转化生长因子 β1 对 TRAIL-R1 信号传导的负向控制涉及 Smad 依赖性的 TRAIL-R1 下调

The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1

抗氧化转录因子核因子 E2 相关因子-2 (Nrf2) 抵消 TGF-β1 介导的胰腺导管上皮细胞生长抑制 -Nrf2 作为 TGF-β1 促肿瘤发生功能的决定因素