日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Ex vivo expansion of melanoma tumor infiltrating lymphocytes leads to a dominant exhausted T cell population with lack of memory markers

体外扩增黑色素瘤肿瘤浸润淋巴细胞会导致以缺乏记忆标志物的耗竭T细胞群为主。

Coppola, Gianfilippo; Kerr, Samuel; Cha, Pei-Chun; Bersenev, Alexey; Olino, Kelly; Kluger, Harriet M; Sznol, Mario; Weiss, Sarah A; Bosenberg, Marcus W; Kleinstein, Steven H; Krause, Diane S; Hurwitz, Michael E; Katz, Samuel G

Circulating tumor-reactive KIR(+)CD8(+) T cells suppress anti-tumor immunity in patients with melanoma

循环肿瘤反应性KIR(+)CD8(+) T细胞抑制黑色素瘤患者的抗肿瘤免疫

Lu, Benjamin Y; Lucca, Liliana E; Lewis, Wesley; Wang, Jiping; Nogueira, Catarina V; Heer, Sebastian; Rayon-Estrada, Violeta; Axisa, Pierre-Paul; Reeves, Sarah M; Buitrago-Pocasangre, Nicholas C; Pham, Giang H; Kojima, Mina L; Wei, Wei; Aizenbud, Lilach; Bacchiocchi, Antonietta; Zhang, Lin; Walewski, Joseph J; Chiang, Veronica; Olino, Kelly; Clune, James; Halaban, Ruth; Kluger, Yuval; Coyle, Anthony J; Kisielow, Jan; Obermair, Franz-Josef; Kluger, Harriet M; Hafler, David A

Lipophilic Statins Deplete GPX4 to Promote Ferroptosis and Sensitize Cancer Cells to Immune Checkpoint Blockade.

亲脂性他汀类药物通过消耗 GPX4 促进铁死亡,使癌细胞对免疫检查点阻断疗法更加敏感。

Talty Ronan, Brooks Veronica T, McGeary Meaghan K, Milette Simon, Zheng Sijin, Flem-Karlsen Karine, Daniels Andrew, Deshmukh Maya, Park Koonam, Caraccio Will, Yan Hong, Echeandia-Francis Caroline, McNamara Madeline, Hong Suyeon, Kirwin David S, Olino Kelly, Johnson Caroline H, Bosenberg Marcus, Micevic Goran, Roy Simon F

Case Report: Complete response to pembrolizumab monotherapy in a geriatric patient with metastatic Merkel cell carcinoma and TNBC

病例报告:一名老年转移性默克尔细胞癌和三阴性乳腺癌患者接受帕博利珠单抗单药治疗后获得完全缓解。

Liu, Jessica; Olino, Kelly; Lustberg, Maryam; Kanowitz, Jane

Use of imiquimod topical therapy for management of malignant melanoma positive margins

咪喹莫特局部治疗在恶性黑色素瘤阳性切缘治疗中的应用

Lewis, Katelyn; Islam, Sara; Alper, David P; Carney, Martin J; Choi, Jennifer; Leventhal, Jonathan; Ariyan, Stephan; Baumann, Raymond; Olino, Kelly; Clune, James

Immunotherapy Initiation at the End of Life in Patients With Metastatic Cancer in the US

美国转移性癌症患者临终免疫治疗的启动

Kerekes, Daniel M; Frey, Alexander E; Prsic, Elizabeth H; Tran, Thuy T; Clune, James E; Sznol, Mario; Kluger, Harriet M; Forman, Howard P; Becher, Robert D; Olino, Kelly L; Khan, Sajid A

Digital spatial proteomic profiling reveals immune checkpoints as biomarkers in lymphoid aggregates and tumor microenvironment of desmoplastic melanoma

数字空间蛋白质组学分析揭示了免疫检查点作为促纤维增生性黑色素瘤淋巴聚集体和肿瘤微环境中的生物标志物

Su, David G; Schoenfeld, David A; Ibrahim, Wael; Cabrejo, Raysa; Djureinovic, Dijana; Baumann, Raymond; Rimm, David L; Khan, Sajid A; Halaban, Ruth; Kluger, Harriet M; Olino, Kelly; Galan, Anjela; Clune, James

Melanocortin-1 Receptor Expression as a Marker of Progression in Melanoma.

黑素皮质素-1受体表达作为黑色素瘤进展的标志物

Su David G, Djureinovic Dijana, Schoenfeld David, Marquez-Nostra Bernadette, Olino Kelly, Jilaveanu Lucia, Kluger Harriet

Immunotherapy utilization in stage IIIA melanoma: less may be more

IIIA期黑色素瘤的免疫疗法应用:少即是多

Frey, Alexander E; Kerekes, Daniel M; Khan, Sajid A; Tran, Thuy T; Kluger, Harriet M; Clune, James E; Ariyan, Stephan; Sznol, Mario; Ishizuka, Jeffrey J; Olino, Kelly L

Causes of death and patterns of metastatic disease at the end of life for patients with advanced melanoma in the immunotherapy era

免疫治疗时代晚期黑色素瘤患者临终时的死亡原因和转移性疾病模式

Lee, Daniel Y; McNamara, Madeline; Yang, Alexander; Yaskolko, Maxim; Kluger, Harriet; Tran, Thuy; Olino, Kelly; Clune, James; Sznol, Mario; Ishizuka, Jeffrey J