Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells
雷帕霉素(mTORC1 抑制剂)可减少 IDH1 突变纤维肉瘤细胞中乳酸和 2-羟基戊二酸癌代谢物的产生
期刊:Journal of Experimental & Clinical Cancer Research
影响因子:11.4
doi:10.1186/s13046-017-0544-y
Zoltán Hujber, Gábor Petővári, Norbert Szoboszlai, Titanilla Dankó, Noémi Nagy, Csilla Kriston, Ildikó Krencz, Sándor Paku, Olivér Ozohanics, László Drahos, András Jeney, Anna Sebestyén
代谢
信号转导
肿瘤
肿瘤细胞
Cell sorting
FCM
WB
mTOR