日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Synthesis and evaluation of 14β-acyl substituted 17-cyclopropylmethyl-7,8-dihydromorphinone derivatives: mixed partial agonists at mu opioid and nociception/orphanin FQ peptide receptors

14β-酰基取代的17-环丙基甲基-7,8-二氢吗啡酮衍生物的合成与评价:μ阿片受体和伤害感受/孤啡肽FQ受体的混合部分激动剂

Ostovar, Mehrnoosh; Olsen, Keith; Cami-Kobeci, Gerta; Traynor, John R; Jeramaz, Luka; Kirton, Stewart B; Husbands, Stephen M

Effectiveness of a Pharmacist-Led Intervention to Reduce Acid Suppression Therapy for Stress Ulcer Prophylaxis in ICUs in China: A Multicenter, Stepped-Wedge, Cluster-Randomized Controlled Trial

药师主导干预降低重症监护病房应激性溃疡预防中抑酸治疗效果的研究:一项多中心、阶梯楔形、整群随机对照试验

Li, Hailong; Zeng, Linan; Xu, Peipei; Olsen, Keith; Granholm, Anders; Jin, Xiaodong; Zhang, Lingli; Guyatt, Gordon

Discovery of highly potent α-keto ester-based peptidomimetic inhibitors of the Hip1 protease for the treatment of Mycobacterium tuberculosis

发现高效的α-酮酯类Hip1蛋白酶肽模拟抑制剂,用于治疗结核分枝杆菌感染

Schumann, Nicholas; Shamma, Farah; Brooks, Cory L; Johnson, Sean J; Yim, Matthew K; Olsen, Keith J; Peña, Karla; Karakousis, Petros C; Abell, Andrew; Goldfarb, Nathan E

Hydrogen-deuterium exchange mass spectrometry of Mtr4 with diverse RNAs reveals substrate-dependent dynamics and interfaces in the arch

利用氢氘交换质谱法研究Mtr4与多种RNA的相互作用,揭示了其在拱形结构中依赖于底物的动力学和界面。

Zhang, Naifu; Olsen, Keith J; Ball, Darby; Johnson, Sean J; D'Arcy, Sheena

Insights into the importance of WPD-loop sequence for activity and structure in protein tyrosine phosphatases

深入探究WPD环序列对蛋白质酪氨酸磷酸酶活性和结构的重要性

Shen, Ruidan; Crean, Rory M; Olsen, Keith J; Corbella, Marina; Calixto, Ana R; Richan, Teisha; Brandão, Tiago A S; Berry, Ryan D; Tolman, Alex; Loria, J Patrick; Johnson, Sean J; Kamerlin, Shina C L; Hengge, Alvan C

The Society of Critical Care Medicine at 50 Years: Interprofessional Practice in Critical Care: Looking Back and Forging Ahead

重症医学会成立50周年:重症监护领域的跨专业实践:回顾过去,展望未来

Kleinpell, Ruth; Grabenkort, W Robert; Boyle, Walter A 3rd; Vines, David L; Olsen, Keith M

Pharmacist-Led Intervention on the Inappropriate Use of Stress Ulcer Prophylaxis Pharmacotherapy in Intensive Care Units: A Systematic review

药师主导的干预措施在重症监护病房中对不恰当使用应激性溃疡预防药物治疗的干预:系统评价

Xu, Peipei; Yi, Qiusha; Wang, Cuitong; Zeng, Linan; Olsen, Keith M; Zhao, Rongsheng; Jiang, Mingyan; Xu, Ting; Zhang, Lingli

Capacity Building for Research in Critical Care: A Pilot Program in the Eastern Mediterranean Region

重症监护研究能力建设:东地中海区域的试点项目

Nazer, Lama H; Kleinpell, Ruth; Olsen, Keith; Hawari, Feras

Mtr4 RNA helicase structures and interactions

Mtr4 RNA解旋酶的结构和相互作用

Olsen, Keith J; Johnson, Sean J

Structural basis of Type IV CRISPR RNA biogenesis by a Cas6 endoribonuclease

Cas6核糖核酸内切酶介导的IV型CRISPR RNA生物合成的结构基础

Taylor, Hannah N; Warner, Emily E; Armbrust, Matthew J; Crowley, Valerie M; Olsen, Keith J; Jackson, Ryan N