Hepatic danger signaling triggers TREM2(+) macrophage induction and drives steatohepatitis via MS4A7-dependent inflammasome activation
肝脏危险信号触发TREM2(+)巨噬细胞的诱导，并通过MS4A7依赖性炎症小体激活驱动脂肪性肝炎。
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.adk1866
Zhou, Linkang; Qiu, Xiaoxue; Meng, Ziyi; Liu, Tongyu; Chen, Zhimin; Zhang, Peng; Kuang, Henry; Pan, Tong; Lu, You; Qi, Ling; Olson, David P; Xu, X Z Shawn; Chen, Y Eugene; Li, Siming; Lin, Jiandie D
巨噬细胞
炎症
炎性小体
炎症/感染
信号转导
TREM2
巨噬细胞
多发性硬化症
细胞生物学
肝炎
炎性小体
免疫/内分泌
