Glucocorticoids rapidly activate cAMP production via Gαs to initiate non-genomic signaling that contributes to one-third of their canonical genomic effects
糖皮质激素通过 Gαs 快速激活 cAMP 的产生,从而启动非基因组信号传导,这占其典型基因组效应的三分之一
期刊:FASEB Journal
影响因子:4.4
doi:10.1096/fj.201902521R
Francisco J Nuñez, Timothy B Johnstone, Maia L Corpuz, Austin G Kazarian, Nicole N Mohajer, Omar Tliba, Reynold A Panettieri Jr, Cynthia Koziol-White, Moom R Roosan, Rennolds S Ostrom
信号转导
ELISA
IHC-P
WB
GPCR/Calcium/cAMP