日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Metabolomic Approaches Reveal the Role of CAR in Energy Metabolism

代谢组学方法揭示CAR在能量代谢中的作用

Fengming Chen, Denise M Coslo, Tao Chen, Limin Zhang, Yuan Tian, Philip B Smith, Andrew D Patterson, Curtis J Omiecinski

In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets

小鼠和人类组成型雄甾烷受体的体内全基因组结合相互作用揭示了新的基因靶点

Ben Niu,Denise M Coslo,Alain R Bataille,Istvan Albert,B Franklin Pugh,Curtis J Omiecinski

Activation of the Constitutive Androstane Receptor by Monophthalates

单邻苯二甲酸酯激活组成型雄甾烷受体

Elizabeth M Laurenzana, Denise M Coslo, M Veronica Vigilar, Anthony M Roman, Curtis J Omiecinski

Phenobarbital and propiconazole toxicogenomic profiles in mice show major similarities consistent with the key role that constitutive androstane receptor (CAR) activation plays in their mode of action

苯巴比妥和丙环唑在小鼠体内的毒理基因组学特征显示出显著的相似性,这与组成型雄甾烷受体(CAR)激活在其作用机制中发挥的关键作用相一致。

Currie, Richard A; Peffer, Richard C; Goetz, Amber K; Omiecinski, Curtis J; Goodman, Jay I

Proteasomal interaction as a critical activity modulator of the human constitutive androstane receptor

蛋白酶体相互作用作为人类组成型雄烷受体的关键活性调节剂

Tao Chen, Elizabeth M Laurenzana, Denise M Coslo, Fengming Chen, Curtis J Omiecinski

Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator

核受体介导的肝毒性作用机制及人体相关性分析:以苯巴比妥为模型组成型雄烷受体(CAR)激活剂的案例研究

Elcombe, Clifford R; Peffer, Richard C; Wolf, Douglas C; Bailey, Jason; Bars, Remi; Bell, David; Cattley, Russell C; Ferguson, Stephen S; Geter, David; Goetz, Amber; Goodman, Jay I; Hester, Susan; Jacobs, Abigail; Omiecinski, Curtis J; Schoeny, Rita; Xie, Wen; Lake, Brian G

Human receptor activation by aroclor 1260, a polychlorinated biphenyl mixture

一种多氯联苯混合物 aroclor 1260 激活人类受体

Banrida Wahlang, K Cameron Falkner, Heather B Clair, Laila Al-Eryani, Russell A Prough, J Christopher States, Denise M Coslo, Curtis J Omiecinski, Matthew C Cave

Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter

内含子DNA元件通过远端上游的替代启动子调控人微粒体环氧化物水解酶基因(EPHX1)的Nrf2化学反应性

Shengzhong Su ,Xi Yang ,Curtis J Omiecinski

Sp1 and Sp3 transcription factors regulate the basal expression of human microsomal epoxide hydrolase (EPHX1) through interaction with the E1b far upstream promoter

Sp1 和 Sp3 转录因子通过与 E1b 远端上游启动子相互作用来调控人微粒体环氧化物水解酶 (EPHX1) 的基础表达。

Shengzhong Su ,Curtis J Omiecinski

Expression of a novel mRNA transcript for human microsomal epoxide hydrolase (EPHX1) is regulated by short open reading frames within its 5'-untranslated region

人微粒体环氧化物水解酶 (EPHX1) 的新型 mRNA 转录本的表达受其 5' 非翻译区内短开放阅读框的调控。

Nguyen, Hong Loan; Yang, Xi; Omiecinski, Curtis J