日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Spatial transcriptomics unveils estrogen-modulated immune responses and structural alterations in the ectocervical mucosa of depot medroxyprogesterone acetate users

空间转录组学揭示了雌激素调节的免疫反应以及使用长效醋酸甲羟孕酮避孕药的女性宫颈外黏膜的结构改变

Kaldhusdal, Vilde; Boger, Mathias Franzen; Tjernlund, Annelie; Burgener, Adam D; Bradley, Frideborg; Lajoie, Julie; Omollo, Kenneth; Kimani, Joshua; Fowke, Keith; Czarnewski, Paulo; Broliden, Kristina

The cervicovaginal microbiome associates with spatially restricted host transcriptional signatures throughout the human ectocervical epithelium and submucosa

宫颈阴道微生物群与人类宫颈外上皮和黏膜下层中空间受限的宿主转录特征相关

Kaldhusdal, Vilde; Franzén Boger, Mathias; Burgener, Adam D; Lajoie, Julie; Omollo, Kenneth; Kimani, Joshua; Tjernlund, Annelie; Fowke, Keith R; Kwon, Douglas S; Edfeldt, Gabriella; Broliden, Kristina

HIV-Exposed Seronegative Female Sex Workers Show Different Cellular Immune Profiles Across the Menstrual Cycle

HIV 暴露但血清阴性的女性性工作者在月经周期中表现出不同的细胞免疫特征

Kowatsch, Monika M; Omollo, Kenneth; Bradley, Frideborg; Månberg, Anna; Nilsson, Peter; Bergström, Sofia; Oyugi, Julius; Kimani, Joshua; Broliden, Kristina; Fowke, Keith R; Lajoie, Julie

Spatial transcriptomics and in situ immune cell profiling of the host ectocervical landscape of HIV infected Kenyan sex working women

对感染艾滋病毒的肯尼亚性工作者的宫颈外膜宿主景观进行空间转录组学和原位免疫细胞分析

Franzén Boger, Mathias; Kaldhusdal, Vilde; Pascual-Reguant, Anna; Kroh, Sandy; Uecker, Ralf; Burgener, Adam D; Lajoie, Julie; Omollo, Kenneth; Kimani, Joshua; Fowke, Keith R; Hauser, Anja E; Tjernlund, Annelie; Broliden, Kristina

Sustained immune activation and impaired epithelial barrier integrity in the ectocervix of women with chronic HIV infection

慢性 HIV 感染女性宫颈外口持续免疫激活和上皮屏障完整性受损

Franzén Boger, Mathias; Hasselrot, Tyra; Kaldhusdal, Vilde; Miranda, Gisele H B; Czarnewski, Paulo; Edfeldt, Gabriella; Bradley, Frideborg; Rexaj, Genta; Lajoie, Julie; Omollo, Kenneth; Kimani, Joshua; Fowke, Keith R; Broliden, Kristina; Tjernlund, Annelie

Estradiol-mediated enhancement of the human ectocervical epithelial barrier correlates with desmoglein-1 expression in the follicular menstrual phase

雌二醇介导的人宫颈外口上皮屏障增强与卵泡期月经阶段的桥粒芯蛋白-1表达相关。

Bradley, Frideborg; Stern, Alexandra; Franzén Boger, Mathias; Mousavian, Zaynab; Dethlefsen, Olga; Kaldhusdal, Vilde; Lajoie, Julie; Omollo, Kenneth; Bergström, Sofia; Månberg, Anna; Nilsson, Peter; Kimani, Joshua; Burgener, Adam D; Tjernlund, Annelie; Sundling, Christopher; Fowke, Keith R; Broliden, Kristina

Vaginal candida infection is associated with host molecular signatures of neutrophil activation in the adjacent ectocervical mucosa in Kenyan sex workers.

肯尼亚性工作者的阴道念珠菌感染与邻近宫颈外口粘膜中中性粒细胞活化的宿主分子特征有关

Hasselrot Tyra, Boger Mathias Franzén, Kaldhusdal Vilde, à hlberg Alexandra, Omollo Kenneth, Lajoie Julie, Kimani Joshua, Tjernlund Annelie, Fowke Keith R, Czarnewski Paulo, Broliden Kristina

Regular Use of Depot Medroxyprogesterone Acetate Causes Thinning of the Superficial Lining and Apical Distribution of Human Immunodeficiency Virus Target Cells in the Human Ectocervix

规律使用醋酸甲羟孕酮缓释剂会导致人宫颈外口表层变薄,并使人类免疫缺陷病毒靶细胞向顶端分布。

Edfeldt, Gabriella; Lajoie, Julie; Röhl, Maria; Oyugi, Julius; Åhlberg, Alexandra; Khalilzadeh-Binicy, Behnaz; Bradley, Frideborg; Mack, Matthias; Kimani, Joshua; Omollo, Kenneth; Wählby, Carolina; Fowke, Keith R; Broliden, Kristina; Tjernlund, Annelie

Differential Elevation of Inflammation and CD4(+) T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate

使用醋酸甲羟孕酮缓释剂的肯尼亚女性性工作者和非性工作者炎症和 CD4(+) T 细胞活化的差异性升高

Omollo, Kenneth; Lajoie, Julie; Oyugi, Julius; Wessels, Jocelyn M; Mwaengo, Dufton; Kimani, Joshua; Kaushic, Charu; Fowke, Keith R

Characterization of the Genital Mucosa Immune Profile to Distinguish Phases of the Menstrual Cycle: Implications for HIV Susceptibility

通过对生殖器黏膜免疫特征的分析来区分月经周期的不同阶段:对艾滋病毒易感性的影响

Boily-Larouche, Geneviève; Lajoie, Julie; Dufault, Brenden; Omollo, Kenneth; Cheruiyot, Juliana; Njoki, Jane; Kowatsch, Monika; Kimani, Makobu; Kimani, Joshua; Oyugi, Julius; Fowke, Keith R