日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Non-redundant roles of the phosphoinositide phosphatases PTEN and PIPP in PI3K/AKT signaling in breast cancer.

磷脂酰肌醇磷酸酶 PTEN 和 PIPP 在乳腺癌 PI3K/AKT 信号传导中发挥着不可替代的作用。

Ooms Lisa M, Ferguson Daniel T, Rodgers Samuel J, Sukhija Karmanpreet K, Jones Emily I, Csolle Mariah P, Yip Hon Yan Kelvin, Daly Roger J, Tiganis Tony, McLean Catriona A, Papa Antonella, Mitchell Christina A

The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer

乳腺癌中 1A 类 PI3K 和 Wnt/β-catenin 偶联信号传导的机制

Rodgers, Samuel J; Mitchell, Christina A; Ooms, Lisa M

A late endosome signaling hub that couples PI3Kα and WNT/β-catenin signaling in breast cancer

乳腺癌中连接PI3Kα和WNT/β-catenin信号通路的晚期内体信号枢纽

Rodgers, Samuel J; Hamila, Sabryn A; Mitchell, Christina A; Ooms, Lisa M

Silencer of death domains (SODD) inhibits skeletal muscle and kidney enriched inositol 5-phosphatase (SKIP) and regulates phosphoinositide 3-kinase (PI3K)/Akt signaling to the actin cytoskeleton

死亡结构域沉默因子(SODD)抑制骨骼肌和肾脏富集的肌醇5-磷酸酶(SKIP),并调节磷脂酰肌醇3-激酶(PI3K)/Akt信号通路对肌动蛋白细胞骨架的影响。

Rahman, Parvin; Huysmans, Richard D; Wiradjaja, Fenny; Gurung, Rajendra; Ooms, Lisa M; Sheffield, David A; Dyson, Jennifer M; Layton, Meredith J; Sriratana, Absorn; Takada, Hidetoshi; Tiganis, Tony; Mitchell, Christina A

Identification of a proline-rich inositol polyphosphate 5-phosphatase (PIPP)•collapsin response mediator protein 2 (CRMP2) complex that regulates neurite elongation.

鉴定出一种富含脯氨酸的肌醇多磷酸 5-磷酸酶 (PIPP) • 塌陷反应介质蛋白 2 (CRMP2) 复合物,该复合物调节神经突的延伸

Astle Megan V, Ooms Lisa M, Cole Adam R, Binge Lauren C, Dyson Jennifer M, Layton Meredith J, Petratos Steven, Sutherland Calum, Mitchell Christina A

A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart

突触蛋白2基因突变导致ENU诱变小鼠品系Mozart出现进行性听力丧失。

Manji, Shehnaaz S M; Williams, Louise H; Miller, Kerry A; Ooms, Lisa M; Bahlo, Melanie; Mitchell, Christina A; Dahl, Hans-Henrik M

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers

肌醇多磷酸4-磷酸酶II调节PI3K/Akt信号通路,并在人类基底样乳腺癌中缺失。

Fedele, Clare G; Ooms, Lisa M; Ho, Miriel; Vieusseux, Jessica; O'Toole, Sandra A; Millar, Ewan K; Lopez-Knowles, Elena; Sriratana, Absorn; Gurung, Rajendra; Baglietto, Laura; Giles, Graham G; Bailey, Charles G; Rasko, John E J; Shields, Benjamin J; Price, John T; Majerus, Philip W; Sutherland, Robert L; Tiganis, Tony; McLean, Catriona A; Mitchell, Christina A

Reactive oxygen species enhance insulin sensitivity

活性氧可增强胰岛素敏感性

Loh, Kim; Deng, Haiyang; Fukushima, Atsushi; Cai, Xiaochu; Boivin, Benoit; Galic, Sandra; Bruce, Clinton; Shields, Benjamin J; Skiba, Beata; Ooms, Lisa M; Stepto, Nigel; Wu, Ben; Mitchell, Christina A; Tonks, Nicholas K; Watt, Matthew J; Febbraio, Mark A; Crack, Peter J; Andrikopoulos, Sofianos; Tiganis, Tony

The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation

肌醇多磷酸5-磷酸酶(PIPP)是磷脂酰肌醇3-激酶依赖性神经突延伸的一种新型调节因子。

Ooms, Lisa M; Fedele, Clare G; Astle, Megan V; Ivetac, Ivan; Cheung, Vanessa; Pearson, Richard B; Layton, Meredith J; Forrai, Ariel; Nandurkar, Harshal H; Mitchell, Christina A