文献库，生知库 | 链接生命科学的每一步

日期影响因子

CRISPR/Cas9 Targeting of Aldehyde Dehydrogenase 1A1 Reveals Heterogeneous Roles in Radiation Response and Redox Stress Across Clonal Lines in Triple-Negative Breast Cancer

利用 CRISPR/Cas9 技术靶向醛脱氢酶 1A1 揭示其在三阴性乳腺癌不同克隆细胞系中对辐射反应和氧化还原应激的异质性作用

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26052303

Ajayi, Grace O; Ma, Aihui; Modarai, Shirin R; Opdenaker, Lynn M; Sims-Mourtada, Jennifer

细胞生物学

发表日期：2025

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B cells enhance IL-1 beta driven invasiveness in triple negative breast cancer

细胞增强 IL-1β 驱动的三阴性乳腺癌侵袭性

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/s41598-025-86064-1

Nicole J Toney, Lynn M Opdenaker, Lisa Frerichs, Shirin R Modarai, Aihui Ma, Holly Archinal, Grace O Ajayi, Jennifer Sims-Mourtada

细胞生物学

发表日期：2025

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Dynamic Organization of Cells in Colonic Epithelium is Encoded by Five Biological Rules

结肠上皮细胞的动态组织由五条生物学规则编码

期刊:Biology of the Cell

影响因子:2.4

doi:10.1111/boc.70017

Boman, Bruce M; Dinh, Thien-Nam; Decker, Keith; Emerick, Brooks; Modarai, Shirin R; Opdenaker, Lynn M; Fields, Jeremy Z; Raymond, Christopher; Schleiniger, Gilberto

细胞生物学

发表日期：2025

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B cells enhance IL-1 beta driven invasiveness in triple-negative breast cancer

细胞增强 IL-1β 驱动的三阴性乳腺癌侵袭性

doi:10.21203/rs.3.rs-5153341/v1

Nicole J Toney, Lynn M Opdenaker, Lisa Frerichs, Shirin R Modarai, Aihui Ma, Holly Archinal, Grace O Ajayi, Jennifer Sims-Mourtada

细胞生物学

发表日期：2024

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CYP26A1 Links WNT and Retinoic Acid Signaling: A Target to Differentiate ALDH+ Stem Cells in APC-Mutant CRC

CYP26A1 连接 WNT 和视黄酸信号：分化 APC 突变型 CRC 中的 ALDH+ 干细胞的靶点

doi:10.3390/cancers16020264

Caroline O B Facey, Victoria O Hunsu, Chi Zhang, Brian Osmond, Lynn M Opdenaker, Bruce M Boman

发育与干细胞

发表日期：2024

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Beyond the Genetic Code: A Tissue Code?

超越基因密码：组织密码？

doi:10.1101/2023.03.05.531161

Boman, Bruce M; Dinh, Thien-Nam; Decker, Keith; Emerick, Brooks; Modarai, Shirin; Opdenaker, Lynn; Fields, Jeremy Z; Raymond, Christopher; Schleiniger, Gilberto

发表日期：2023

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Differential miRNA Expression Contributes to Emergence of Multiple Cancer Stem Cell Subpopulations in Human Colorectal Cancer

差异 miRNA 表达导致人类结直肠癌中多种癌症干细胞亚群的出现

doi:10.1101/2023.02.06.527341

Victoria A Stark, Caroline O B Facey, Lynn Opdenaker, Jeremy Z Fields, Bruce M Boman

发育与干细胞

发表日期：2023

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Tumor-B-cell interactions promote isotype switching to an immunosuppressive IgG4 antibody response through upregulation of IL-10 in triple negative breast cancers

肿瘤-B 细胞相互作用通过上调三阴性乳腺癌中的 IL-10 促进同种型转换为免疫抑制 IgG4 抗体反应

期刊:Journal of Translational Medicine

影响因子:6.1

doi:10.1186/s12967-022-03319-5

Nicole J Toney, Lynn M Opdenaker, Kader Cicek, Lisa Frerichs, Christopher Ryan Kennington, Samuel Oberly, Holly Archinal, Rajasekharan Somasundaram, Jennifer Sims-Mourtada

发表日期：2022

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Precise and error-prone CRISPR-directed gene editing activity in human CD34+ cells varies widely among patient samples

人类 CD34+ 细胞中 CRISPR 定向基因编辑的精确度和易错性在不同患者样本中存在很大差异

期刊:Gene Therapy

影响因子:4.6

doi:10.1038/s41434-020-00192-z

Shirin R Modarai, Sambee Kanda, Kevin Bloh, Lynn M Opdenaker, Eric B Kmiec

细胞生物学

发表日期：2021

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APC mutations in human colon lead to decreased neuroendocrine maturation of ALDH+ stem cells that alters GLP-2 and SST feedback signaling: Clue to a link between WNT and retinoic acid signalling in colon cancer development

人类结肠中的 APC 突变导致 ALDH+ 干细胞神经内分泌成熟度降低，从而改变 GLP-2 和 SST 反馈信号：WNT 与视黄酸信号在结肠癌发展中存在联系的线索

期刊:PLoS One

影响因子:2.9

doi:10.1371/journal.pone.0239601

Tao Zhang, Koree Ahn, Brooks Emerick, Shirin R Modarai, Lynn M Opdenaker, Juan Palazzo, Gilberto Schleiniger, Jeremy Z Fields, Bruce M Boman

发育与干细胞

发表日期：2020

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