日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Characterization of early pathogenesis in the SOD1(G93A) mouse model of ALS: part II, results and discussion

SOD1(G93A) ALS小鼠模型早期发病机制的特征分析:第二部分,结果与讨论

Vinsant, Sharon; Mansfield, Carol; Jimenez-Moreno, Ramon; Del Gaizo Moore, Victoria; Yoshikawa, Masaaki; Hampton, Thomas G; Prevette, David; Caress, James; Oppenheim, Ronald W; Milligan, Carol

Motor neuron trophic factors: therapeutic use in ALS?

运动神经元营养因子:在肌萎缩侧索硬化症(ALS)治疗中的应用?

Gould, Thomas W; Oppenheim, Ronald W

Characterization of sensory neurons in the dorsal root ganglia of Bax-deficient mice.

对缺乏 Bax 的小鼠背根神经节中的感觉神经元进行表征

Suzuki Hiromichi, Aoyama Youhei, Senzaki Kouji, Vincler Michelle, Wittenauer Shannon, Yoshikawa Masaaki, Ozaki Shigeru, Oppenheim Ronald W, Shiga Takashi

Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy

体内缺乏Apaf-1的发育中的有丝分裂后哺乳动物神经元会通过一种不依赖于caspase的非凋亡途径(涉及自噬)发生程序性细胞死亡。

Oppenheim, Ronald W; Blomgren, Klas; Ethell, Douglas W; Koike, Masato; Komatsu, Masaaki; Prevette, David; Roth, Kevin A; Uchiyama, Yasuo; Vinsant, Sharon; Zhu, Changlian

The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes

胶质细胞系衍生神经营养因子对脊髓运动神经元的神经营养作用仅限于梭内运动神经元亚型。

Gould, Thomas W; Yonemura, Shigenobu; Oppenheim, Ronald W; Ohmori, Shiho; Enomoto, Hideki

Misplacement of Purkinje cells during postnatal development in Bax knock-out mice: a novel role for programmed cell death in the nervous system?

Bax基因敲除小鼠出生后发育过程中浦肯野细胞错位:程序性细胞死亡在神经系统中的新功能?

Jung, A-Rong; Kim, Tae Woo; Rhyu, Im Joo; Kim, Hyun; Lee, Young Don; Vinsant, Sharon; Oppenheim, Ronald W; Sun, Woong

The lack of effect of specific overexpression of IGF-1 in the central nervous system or skeletal muscle on pathophysiology in the G93A SOD-1 mouse model of ALS

在G93A SOD-1 ALS小鼠模型中,中枢神经系统或骨骼肌中IGF-1的特异性过表达对病理生理过程没有影响。

Messi, Maria Laura; Clark, Heather M; Prevette, David M; Oppenheim, Ronald W; Delbono, Osvaldo

Exogenous delivery of heat shock protein 70 increases lifespan in a mouse model of amyotrophic lateral sclerosis.

外源性输送热休克蛋白 70 可延长肌萎缩侧索硬化症小鼠模型的寿命

Gifondorwa David J, Robinson Mac B, Hayes Crystal D, Taylor Anna R, Prevette David M, Oppenheim Ronald W, Caress James, Milligan Carolanne E

Complete dissociation of motor neuron death from motor dysfunction by Bax deletion in a mouse model of ALS

在ALS小鼠模型中,Bax基因敲除导致运动神经元死亡与运动功能障碍完全分离。

Gould, Thomas W; Buss, Robert R; Vinsant, Sharon; Prevette, David; Sun, Woong; Knudson, C Michael; Milligan, Carol E; Oppenheim, Ronald W

Neuromuscular development in the absence of programmed cell death: phenotypic alteration of motoneurons and muscle

在没有程序性细胞死亡的情况下,神经肌肉发育:运动神经元和肌肉的表型改变

Buss, Robert R; Gould, Thomas W; Ma, Jianjun; Vinsant, Sharon; Prevette, David; Winseck, Adam; Toops, Kimberly A; Hammarback, James A; Smith, Thomas L; Oppenheim, Ronald W