A potent and selective small-molecule inhibitor for the lymphoid-specific tyrosine phosphatase (LYP), a target associated with autoimmune diseases.
一种强效且选择性的小分子抑制剂,可抑制淋巴细胞特异性酪氨酸磷酸酶 (LYP),LYP 是与自身免疫性疾病相关的靶点
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm400248c
He Yantao, Liu Sijiu, Menon Ambili, Stanford Stephanie, Oppong Emmanuel, Gunawan Andrea M, Wu Li, Wu Dennis J, Barrios Amy M, Bottini Nunzio, Cato Andrew C B, Zhang Zhong-Yin