日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Precision medicine in type 2 diabetes: targeting SGLT2 inhibitor treatment for kidney protection

2型糖尿病精准医疗:靶向SGLT2抑制剂治疗以保护肾脏

Jansz, Thijs T; Young, Katherine G; Hopkins, Rhian; McGovern, Andrew P; Shields, Beverley M; Hattersley, Andrew T; Jones, Angus G; Pearson, Ewan R; Bingham, Coralie; Oram, Richard A; Dennis, John M

Bi-allelic variants in the non-protein-coding minor spliceosome components RNU6ATAC and RNU4ATAC cause syndromic monogenic autoimmune diabetes

非蛋白质编码的次要剪接体组分 RNU6ATAC 和 RNU4ATAC 的双等位基因变异会导致综合征型单基因自身免疫性糖尿病

Johnson, Matthew B; Russ-Silsby, James; Blair, Paul A; Govier, Molly; Bonfield, Georgia; Domingo-Vila, Clara; Wakeling, Matthew N; Oram, Richard A; Flanagan, Sarah E; Tree, Timothy I M; Patel, Kashyap A; Hattersley, Andrew T; De Franco, Elisa

Development and Validation of a Type 1 Diabetes Multi-Ancestry Polygenic Score

1型糖尿病多祖源多基因评分的开发与验证

Deutsch, Aaron J; Bell, Andrew S; Michalek, Dominika A; Burkholder, Adam B; Nam, Stella; Kreienkamp, Raymond J; Sharp, Seth A; Huerta-Chagoya, Alicia; Mandla, Ravi; Nanjala, Ruth; Luo, Yang; Oram, Richard A; Florez, Jose C; Onengut-Gumuscu, Suna; Rich, Stephen S; Ng, Maggie C Y; Motsinger-Reif, Alison A; Manning, Alisa K; Mercader, Josep M; Udler, Miriam S

Type 2 Diabetes Genetic Risk and Type 1 Diabetes Heterogeneity and Progression

2型糖尿病遗传风险与1型糖尿病的异质性和进展

Triolo, Taylor M; Sosenko, Jay M; Cuthbertson, David; Oram, Richard A; Parikh, Hemang M; Steck, Andrea K; Sims, Emily K; Jacobsen, Laura M; Nathan, Brandon; Templeman, Erin L; Onengut-Gumuscu, Suna; Evans-Molina, Carmella; Rich, Stephen S; Atkinson, Mark A; Redondo, Maria J

Biallelic Pathogenic Variants in IL2RA Cause Neonatal-Onset Monogenic Autoimmune Diabetes

IL2RA基因的双等位致病变异导致新生儿期发病的单基因自身免疫性糖尿病

Bonfield, Georgia; Russ-Silsby, James; Ramchand, Suraj; Luckett, Amber M; Wakeling, Matthew N; Kulkarni, Abhishek; Nagesh, V Sri; Deeb, Asma; Ravikumar, K G; Nguyen, Phuong T K; Hattersley, Andrew T; Oram, Richard A; Flanagan, Sarah E; De Franco, Elisa; Johnson, Matthew B

Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes

自身免疫性疾病的个人或家族史与未来发生1型糖尿病的关联

Thomas, Nick; Vaidya, Bijay; Leslie, Richard David; Agardh, Daniel; Oram, Richard; Dabelea, Dana; Singh, Arunjot; Chantzichristos, Dimitrios; Rewers, Marian

Genetic Risk and Transition Through Preclinical Stages of Type 1 Diabetes

遗传风险与1型糖尿病临床前期阶段的转变

Steck, Andrea K; Parikh, Hemang M; Triolo, Taylor M; Ferrat, Lauric; You, Lu; Gottlieb, Peter A; Oram, Richard A; Onengut-Gumuscu, Suna; Krischer, Jeffrey P; Rich, Stephen S; Redondo, Maria J

Impact of Metagenomic Next-Generation Sequencing on Antibiotic Management in Pediatric Patients

宏基因组二代测序对儿科患者抗生素管理的影响

Gonzalez, Ariel; Argotsinger, Jill; Oram, Ronda J; Miller, Jessica L

The More Than Words® parent-delivered program for autistic children and those with social communication challenges: a single-arm pragmatic feasibility trial

“超越言语®”家长主导型自闭症儿童及社交沟通障碍儿童项目:一项单组实用性可行性试验

Binns, Amanda V; Tucker, Patricia; Denusik, Lauren; Rajesh Kumar, Vipula; Oram, Janis

The Impact of Ancestry on Performance of Type 1 Diabetes Genetic Risk Scores: High Discrimination Performance Is Maintained in African Ancestry Populations, but Population-Specific Thresholds May Improve Risk Prediction

祖源对1型糖尿病遗传风险评分性能的影响:在非洲裔人群中保持了较高的区分度,但针对特定人群的阈值可能有助于提高风险预测能力。

Squires, Steven; Katte, Jean Claude; Dabelea, Dana; Pihoker, Catherine; Divers, Jasmin; Sobngwi, Eugene; Nyirenda, Moffat J; Kreienkamp, Raymond J; Liese, Angela D; Shah, Amy S; Dolan, Lawrence; Reynolds, Kristi; Redondo, Maria J; Hagopian, William; Fatumo, Segun; Dehayem, Mesmin Y; Hattersley, Andrew T; Weedon, Michael N; Jones, Angus; Oram, Richard A