日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Machine perception liquid biopsy identifies brain tumours via systemic immune and tumour microenvironment signature

机器感知液体活检通过系统免疫和肿瘤微环境特征识别脑肿瘤

Goerzen, Dana; Kim, Mijin; Schroff, Chanel; Hoang, Margaret Ngoc; Wollowitz, Jaina Sarris; Kolb, August; Walshon, Jordain P; McCortney, Kathleen; Horbinski, Craig; Galbraith, Kristyn; Raoof, Sana; Snuderl, Matija; Ordureau, Alban; Heller, Daniel A

mTORC1 regulates the pyrimidine salvage pathway by controlling UCK2 turnover via the CTLH-WDR26 E3 ligase.

mTORC1 通过 CTLH-WDR26 E3 连接酶控制 UCK2 的周转来调节嘧啶补救途径

Pham Brittany Q, Yi Sang Ah, Ordureau Alban, An Heeseon

Activity-based probes and chemical proteomics uncover the biological impact of targeting HMG-CoA Synthase 1 in the mevalonate pathway

基于活性的探针和化学蛋白质组学揭示了靶向甲羟戊酸途径中HMG-CoA合成酶1的生物学影响。

Yi, Sang Ah; Sun, Liang; Rao, Yi; Ordureau, Alban; Lewis, Jason S; An, Heeseon

Micronuclear collapse from oxidative damage

氧化损伤导致的微核崩解

Di Bona, Melody; Chen, Yanyang; Agustinus, Albert S; Mazzagatti, Alice; Duran, Mercedes A; Deyell, Matthew; Bronder, Daniel; Hickling, James; Hong, Christy; Scipioni, Lorenzo; Tedeschi, Giulia; Martin, Sara; Li, Jun; Ruzgaitė, Aušrinė; Riaz, Nadeem; Shah, Parin; D'Souza, Edridge K; Brodtman, D Zack; Sidoli, Simone; Diplas, Bill; Jalan, Manisha; Lee, Nancy Y; Ordureau, Alban; Izar, Benjamin; Laughney, Ashley M; Powell, Simon; Gratton, Enrico; Santaguida, Stefano; Maciejowski, John; Ly, Peter; Jeitner, Thomas M; Bakhoum, Samuel F

The ribotoxic stress response drives UV-mediated cell death.

核糖体毒性应激反应驱动紫外线介导的细胞死亡

Sinha Niladri K, McKenney Connor, Yeow Zhong Y, Li Jeffrey J, Nam Ki Hong, Yaron-Barir Tomer M, Johnson Jared L, Huntsman Emily M, Cantley Lewis C, Ordureau Alban, Regot Sergi, Green Rachel

mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway.

mTORC1-CTLH E3 连接酶通过 Pro/N-降解途径调节 HMG-CoA 合成酶 1 的降解

Yi Sang Ah, Sepic Sara, Schulman Brenda A, Ordureau Alban, An Heeseon

Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons

脑源性自噬体分析揭示了神经元中基础自噬对富含核质的线粒体片段的吞噬作用

Goldsmith, Juliet; Ordureau, Alban; Harper, J Wade; Holzbaur, Erika L F

Ubiquitin system mutations in neurological diseases

神经系统疾病中的泛素系统突变

Zenge, Colin; Ordureau, Alban

How does the neuronal proteostasis network react to cellular cues?

神经元蛋白质稳态网络如何对细胞信号做出反应?

Nam, Ki Hong; Ordureau, Alban

Pharmacological PINK1 activation ameliorates Pathology in Parkinson's Disease models

药理学激活PINK1可改善帕金森病模型中的病理

Hertz, Nicholas; Chin, Randall; Rakhit, Rishi; Ditsworth, Dara; Wang, Chengzhong; Bartholomeus, Johan; Liu, Song; Mody, Akash; Laihsu, Alex; Eastes, Andrea; Tai, Chao; Kim, Roy; Li, Jessica; Khasnavis, Saurabh; Rafalski, Victoria; Heerendeen, Donald; Garda, Virginia; Phung, Jennie; de Roulet, Daniel; Ordureau, Alban; Harper, J Wade; Johnstone, Shawn; Stöhr, Jan