The C-terminal peptide of CCL21 drastically augments CCL21 activity through the dendritic cell lymph node homing receptor CCR7 by interaction with the receptor N-terminus
CCL21 的 C 端肽通过与受体 N 端相互作用,通过树突状细胞淋巴结归巢受体 CCR7 显著增强 CCL21 活性
期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-021-03930-7
Astrid Sissel Jørgensen, Emma Probst Brandum, Jeppe Malthe Mikkelsen, Klaudia A Orfin, Ditte Rahbæk Boilesen, Kristoffer Lihme Egerod, Natasha A Moussouras, Frederik Vilhardt, Pawel Kalinski, Per Basse, Yen-Hsi Chen, Zhang Yang, Michael B Dwinell, Brian F Volkman, Christopher T Veldkamp, Peter Johan