日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Prostate cancer-derived holoclones: a novel and effective model for evaluating cancer stemness

前列腺癌衍生的全克隆:一种评估癌症干细胞的新型有效模型

Louise Flynn #, Martin P Barr #, Anne-Marie Baird #, Paul Smyth, Orla M Casey, Gordon Blackshields, John Greene, Stephen R Pennington, Emily Hams, Padraic G Fallon, John O'Leary, Orla Sheils, Stephen P Finn

Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression

mir-222 和 mir-25 表达改变会影响转化的正常和间变性甲状腺细胞中的多种基因表达变化,并影响 MEK 和 TRAIL 蛋白表达

Sinéad T Aherne, Paul Smyth, Michael Freeley, Leila Smith, Cathy Spillane, John O'Leary, Orla Sheils

Pluripotency markers are differentially induced by MEK inhibition in thyroid and melanoma BRAFV600E cell lines

MEK 抑制在甲状腺和黑色素瘤 BRAFV600E 细胞系中诱导了不同的多能性标志物

Emma R Dorris, Gordon Blackshields, Gary Sommerville, Mohsen Alhashemi, Andrew Dias, Victoria McEneaney, Paul Smyth, John J O'Leary, Orla Sheils

Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells

CD19(+) CD1d(hi) B 细胞上 TLR7 的连接可通过调节性 T 细胞抑制过敏性肺部炎症

Adnan R Khan, Sylvie Amu, Sean P Saunders, Emily Hams, Gordon Blackshields, Martin O Leonard, Casey T Weaver, Tim Sparwasser, Orla Sheils, Padraic G Fallon

Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium

Onconetwork 联盟开发基于半导体测序的结肠癌和肺癌基因分型面板

Bastiaan B J Tops, Nicola Normanno, Henriette Kurth, Eliana Amato, Andrea Mafficini, Nora Rieber, Delphine Le Corre, Anna Maria Rachiglio, Anne Reiman, Orla Sheils, Christoph Noppen, Ludovic Lacroix, Ian A Cree, Aldo Scarpa, Marjolijn J L Ligtenberg, Pierre Laurent-Puig9

An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines

人类多能和无能干细胞系中 SOX2 microRNA 反应程序的综合分析

Sebastian F Vencken, Praveen Sethupathy, Gordon Blackshields, Cathy Spillane, Salah Elbaruni, Orla Sheils, Michael F Gallagher, John J O'Leary

Pre-Treatment of platinum resistant ovarian cancer cells with an MMP-9/MMP-2 inhibitor prior to cisplatin enhances cytotoxicity as determined by high content screening

高内涵筛选结果表明,在顺铂治疗之前使用 MMP-9/MMP-2 抑制剂对铂耐药卵巢癌细胞进行预处理可增强细胞毒性

Alexandros Laios, Bashir M Mohamed, Lynn Kelly, Richard Flavin, Stephen Finn, Lynda McEvoy, Michael Gallagher, Cara Martin, Orla Sheils, Martina Ring, Anthony Davies, Margaret Lawson, Noreen Gleeson, Tom D'Arcy, Charles d'Adhemar, Lucy Norris, Ream Langhe, Feras Abu Saadeh, John J O'Leary, Sharon A

ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells

ret/PTC-1 表达改变甲状腺滤泡细胞的免疫特征

Karen Denning, Paul Smyth, Susanne Cahill, Jinghuan Li, Richard Flavin, Sinead Aherne, John J O' Leary, Orla Sheils