日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stressed stability and protective efficacy of lead lyophilized formulations of ID93+GLA-SE tuberculosis vaccine

对ID93+GLA-SE结核病疫苗先导冻干制剂的稳定性及保护效力进行了强调。

Archer, Michelle C; McCollum, Joseph; Press, Christopher; Dutill, Timothy S; Liang, Hong; Fedor, Dawn; Kapilow-Cohen, Liam; Gerhardt, Alana; Phan, Tony; Trappler, Edward H; Orr, Mark T; Kramer, Ryan M; Fox, Christopher B

Formulated Phospholipids as Non-Canonical TLR4 Agonists

配制磷脂作为非经典TLR4激动剂

Liang, Hong; Lykins, William R; Seydoux, Emilie; Guderian, Jeffrey A; Phan, Tony; Fox, Christopher B; Orr, Mark T

Optimizing a Multi-Component Intranasal Entamoeba Histolytica Vaccine Formulation Using a Design of Experiments Strategy.

利用实验设计策略优化多组分鼻内溶组织内阿米巴疫苗制剂

Abhyankar Mayuresh M, Orr Mark T, Kinsey Robert, Sivananthan Sandra, Nafziger Andrew J, Oakland David N, Young Mary K, Farr Laura, Uddin Md Jashim, Leslie Jhansi L, Burgess Stacey L, Liang Hong, De Lima Ines, Larson Elise, Guderian Jeffrey A, Lin Susan, Kahn Aaron, Ghosh Prakash, Reed Sierra, Tomai Mark A, Pedersen Karl, Petri William A Jr, Fox Christopher B

Preclinical optimization of an enterotoxigenic Escherichia coli adjuvanted subunit vaccine using response surface design of experiments.

利用响应面实验设计对肠毒素性大肠杆菌佐剂亚单位疫苗进行临床前优化

Poncet David, Hessler Catherine, Liang Hong, Gautheron Sylviane, Sergent Michelle, Rintala Nicholas D, Seydoux Emilie, Huang Po-Wei D, Argilla David, Ruiz Sophie, Heinrichs Jon, Maciel Milton Jr, Orr Mark T

The TLR4 agonist adjuvant SLA-SE promotes functional mucosal antibodies against a parenterally delivered ETEC vaccine

TLR4激动剂佐剂SLA-SE可促进针对肠外给药的ETEC疫苗的功能性黏膜抗体的产生。

Liang, Hong; Poncet, David; Seydoux, Emilie; Rintala, Nicholas D; Maciel, Milton Jr; Ruiz, Sophie; Orr, Mark T

AS03 stresses out macrophages: Commentary on 'Activation of the endoplasmic reticulum stress sensor IRE1α by the vaccine adjuvant AS03 contributes to its immunostimulatory properties'

AS03 使巨噬细胞承受压力:对“疫苗佐剂 AS03 激活内质网应激传感器 IRE1α 有助于其发挥免疫刺激作用”一文的评论

Orr, Mark T; Fox, Christopher B

Development of a thermostable nanoemulsion adjuvanted vaccine against tuberculosis using a design-of-experiments approach

采用实验设计方法开发一种耐热纳米乳佐剂抗结核疫苗

Kramer, Ryan M; Archer, Michelle C; Orr, Mark T; Dubois Cauwelaert, Natasha; Beebe, Elyse A; Huang, Po-Wei D; Dowling, Quinton M; Schwartz, Alicia M; Fedor, Dawn M; Vedvick, Thomas S; Fox, Christopher B

Enhanced Anti-Mycobacterium tuberculosis Immunity over Time with Combined Drug and Immunotherapy Treatment

药物联合免疫疗法可增强抗结核分枝杆菌免疫力

Larsen, Sasha E; Baldwin, Susan L; Orr, Mark T; Reese, Valerie A; Pecor, Tiffany; Granger, Brian; Dubois Cauwelaert, Natasha; Podell, Brendan K; Coler, Rhea N

A structure-function approach to optimizing TLR4 ligands for human vaccines

利用结构-功能方法优化用于人类疫苗的TLR4配体

Carter, Darrick; Fox, Christopher B; Day, Tracey A; Guderian, Jeffrey A; Liang, Hong; Rolf, Tom; Vergara, Julie; Sagawa, Zachary K; Ireton, Greg; Orr, Mark T; Desbien, Anthony; Duthie, Malcolm S; Coler, Rhea N; Reed, Steven G

Antigen presentation by B cells guides programing of memory CD4(+) T-cell responses to a TLR4-agonist containing vaccine in mice

在小鼠体内,B细胞呈递抗原可引导记忆性CD4(+) T细胞对含TLR4激动剂疫苗的应答程序化。

Dubois Cauwelaert, Natasha; Baldwin, Susan L; Orr, Mark T; Desbien, Anthony L; Gage, Emily; Hofmeyer, Kimberly A; Coler, Rhea N