日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cryo-EM Structure of the FtsH Periplasmic Domain Reveals Functional Dynamics

FtsH周质结构域的冷冻电镜结构揭示其功能动态

Göc, Günce; Yadav, Sathish K N; Orriss, George; Borucu, Ufuk; Berger, Imre; Schaffitzel, Christiane; Kabasakal, Burak V

Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies

豪猪抑制是一种很有前景的治疗严重硬化性骨病的药物疗法。

Dreyer, Timothy J; Keen, Jacob A C; Wells, Leah M; Hopkinson, Mark; Orriss, Isabel R; Holdsworth, Gill; Pitsillides, Andrew A; Roberts, Scott J

Dynamic RNA binding and unfolding by nonsense-mediated mRNA decay factor UPF2

无义介导的mRNA衰变因子UPF2介导的动态RNA结合和解折叠

Szeto, Jenn-Yeu A; Vega, Mirella Vivoli; Mailliot, Justine; Orriss, George; Sun, Lingling; Bufton, Joshua C; Powers, Kyle T; Yadav, Sathish K N; Berger, Imre; Schaffitzel, Christiane

The microRNA-455 null mouse shows dysregulated bone turnover

microRNA-455 基因敲除小鼠表现出骨代谢紊乱。

Niu, Lingzi; Swingler, Tracey E; Suelzu, Caterina; Ersek, Adel; Orriss, Isabel R; Barter, Matthew J; Hayman, Dan J; Young, David A; Horwood, Nicole; Clark, Ian M

Stable Sulforaphane Targets the Early Stages of Osteoclast Formation to Engender a Lasting Functional Blockade of Osteoclastogenesis

稳定的萝卜硫素靶向破骨细胞形成的早期阶段,对破骨细胞生成产生持久的功能性阻断

Polymnia Louka, Isabel R Orriss, Andrew A Pitsillides

β,γ-Methylene-ATP and its metabolite medronic acid affect both arterial media calcification and bone mineralization in non-CKD and CKD rats

β,γ-亚甲基-ATP及其代谢产物美屈酸对非CKD和CKD大鼠的动脉中层钙化和骨矿化均有影响。

Opdebeeck, Britt; Van den Branden, Astrid; Adriaensen, Saar; Orriss, Isabel R; Patel, Jessal J; Geryl, Hilde; Zwijsen, Kathleen; D'Haese, Patrick C; Verhulst, Anja

Pathological calcification in canine tendon-derived cells is modulated by extracellular ATP

犬肌腱衍生细胞的病理性钙化受细胞外ATP调控

Zamboulis, Danae E; Marr, Neil; Moustafa, Alaa; Meeson, Richard; Orriss, Isabel R; Thorpe, Chavaunne T

Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects in primary cultures of osteoblasts and osteoclasts

有证据表明焦磷酸盐作为细胞外信号分子,在成骨细胞和破骨细胞的原代培养物中发挥直接的功能作用

Lucie E Bourne, Bethan K Davies, Jose Luis Millan, Timothy R Arnett, Caroline P D Wheeler-Jones, Jacob A C Keen, Scott J Roberts, Isabel R Orriss

A Machine Learning-Based Image Segmentation Method to Quantify In Vitro Osteoclast Culture Endpoints

基于机器学习的图像分割方法量化体外破骨细胞培养终点

Bethan K Davies, Andrew P Hibbert, Scott J Roberts, Helen C Roberts, Jennifer C Tickner, Gill Holdsworth, Timothy R Arnett, Isabel R Orriss

Modulation of osteoblast differentiation and function by the P2X4 receptor

P2X4受体对成骨细胞分化和功能的调节

Orriss, Isabel R; Davies, Bethan K; Bourne, Lucie E; Arnett, Timothy R