日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An increased throughput workflow to identify ion transport and membrane lysis agents for antimicrobial discovery

提高工作流程通量,以鉴定用于抗菌药物发现的离子转运剂和膜裂解剂。

Yang, Kylie; Marsh, Caleb; White, Lisa J; Molyneux, Fergus W; Allam, Thomas L; Popoola, Precious I A; Keers, Olivia B; Rice, Matthew; Hilton, Kira L F; Kotak, Hiral A; Sutton, J Mark; Ortega-Roldan, Jose L; Hind, Charlotte K; Hiscock, Jennifer R; Haynes, Cally J E

Towards the development of supramolecular self-associating amphiphiles as antibiofilm agents against Pseudomonas aeruginosa and Candida albicans biofilms

开发超分子自缔合两亲分子作为抗铜绿假单胞菌和白色念珠菌生物膜的抗生物膜剂

Hilton, Kira L F; Steyn, Hendrik J F; Luthuli, Kusasalethu S; Rice, Matthew; Streather, Bree R; Sweeney, Esther; White, Lisa J; Morgan, Findley R; Rankin, Jennifer; Baker, Jennifer; Bennett, Charlotte; Wilson, Hollie B; Hailey, Perry A; Garrett, Michelle D; Ortega-Roldan, Jose L; Sutton, J Mark; Hind, Charlotte K; Pohl, Carolina H; Hiscock, Jennifer R

Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides

发现和合理诱变蛋氨酸亚砜还原酶生物催化剂以扩大手性亚砜动力学拆分的底物范围

Anselmi, Silvia; Carvalho, Alexandra T P; Serrano-Sanchez, Angela; Ortega-Roldan, Jose L; Caswell, Jill; Omar, Iman; Perez-Ortiz, Gustavo; Barry, Sarah M; Moody, Thomas S; Castagnolo, Daniele

Cell Survival Enabled by Leakage of a Labile Metabolic Intermediate

不稳定代谢中间体的泄漏促进细胞存活

Encarnación Medina-Carmona ,Luis I Gutierrez-Rus ,Fadia Manssour-Triedo ,Matilda S Newton ,Gloria Gamiz-Arco ,Antonio J Mota ,Pablo Reiné ,Juan Manuel Cuerva ,Mariano Ortega-Muñoz ,Eduardo Andrés-León ,Jose Luis Ortega-Roldan ,Burckhard Seelig ,Beatriz Ibarra-Molero ,Jose M Sanchez-Ruiz

Establishing the selective phospholipid membrane coordination, permeation and lysis properties for a series of 'druggable' supramolecular self-associating antimicrobial amphiphiles

建立一系列“可成药”超分子自缔合抗菌两亲分子的选择性磷脂膜配位、渗透和溶解特性

Boles, Jessica E; Bennett, Charlotte; Baker, Jennifer; Hilton, Kira L F; Kotak, Hiral A; Clark, Ewan R; Long, Yifan; White, Lisa J; Lai, Hin Yuk; Hind, Charlotte K; Sutton, J Mark; Garrett, Michelle D; Cheasty, Anne; Ortega-Roldan, Jose L; Charles, Mark; Haynes, Cally J E; Hiscock, Jennifer R

A Zn2+-triggered two-step mechanism of CLIC1 membrane insertion and activation into chloride channels

CLIC1 膜插入和激活氯离子通道的 Zn2+ 触发的两步机制

Varela, Lorena; Hendry, Alex C; Cassar, Joseph; Martin-Escolano, Ruben; Cantoni, Diego; Ossa, Felipe; Edwards, John C; Abdul-Salam, Vahitha; Ortega-Roldan, Jose L

Establishing a Metabolite Extraction Method to Study the Metabolome of Blastocystis Using NMR

建立代谢物提取方法,利用 NMR 研究芽囊原虫代谢组

Jamie M Newton, Emma L Betts, Lyto Yiangou, Jose Ortega Roldan, Anastasios D Tsaousis, Gary S Thompson