日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combination radiation and αPD-L1 enhance tumor control by stimulating CD8+ PD-1+ TCF-1+ T cells in the tumor-draining lymph node

联合放疗和αPD-L1可通过刺激肿瘤引流淋巴结中的CD8+PD-1+TCF-1+T细胞来增强肿瘤控制。

Shen, Yang; Connolly, Erin; Aiello, Meili; Zhou, Chengjing; Chappa, Prasanthi; Song, Haorui; Tippitak, Patan; Clark, Tarralyn; Cardenas, Maria; Prokhnevska, Nataliya; Mariniello, Annapaola; De Bruyker, Isabelle; Pagadala, Meghana S; Dhere, Vishal R; Rafiq, Sarwish; Kesarwala, Aparna H; Orthwein, Alexandre; Thomas, Susan N; Zhang, Shirley L; Khan, Mohammad K; Dixon, J Brandon; Lesinski, Gregory B; Lowe, Michael C; Kissick, Haydn; Yu, David S; Paulos, Chrystal M; Schmitt, Nicole C; Buchwald, Zachary S

Structural elements of cyanobacterial co-factor-independent phosphoglycerate mutase that mediate regulation by PirC

蓝藻辅因子非依赖性磷酸甘油酸变位酶的结构元件介导PirC的调控

Orthwein, Tim; Alford, Janette T; Becker, Nathalie Sofie; Fink, Phillipp; Forchhammer, Karl

The TetR-like regulator Sco4385 and Crp-like regulator Sco3571 modulate heterologous production of antibiotics in Streptomyces coelicolor M512

TetR样调节因子Sco4385和Crp样调节因子Sco3571调控链霉菌M512中抗生素的异源生产

Wilcken, Sarah; Koutsandrea, Panagiota-Hanna; Bakker, Tomke; Kulik, Andreas; Orthwein, Tim; Franz-Wachtel, Mirita; Harbig, Theresa; Nieselt, Kay Katja; Forchhammer, Karl; Brötz-Oesterhelt, Heike; Macek, Boris; Mordhorst, Silja; Kaysser, Leonard; Gust, Bertolt

The E3 ubiquitin ligase Herc1 modulates the response to nucleoside analogs in acute myeloid leukemia.

E3泛素连接酶Herc1调节急性髓系白血病对核苷类似物的反应

Jankovic Maja, Poon William W L, Gonzales-Losada Cristobal, Vazquez Gabriela Galicia, Sharif-Askari Bahram, Ding Yi, Craplet-Desombre Constance, Ilie Alexandru, Shi Jiantao, Wang Yongjie, Jayavelu Ashok Kumar, Orthwein Alexandre, Mercier François Émile

An E3 ubiquitin ligase localization screen uncovers DTX2 as a novel ADP-ribosylation-dependent regulator of DNA double-strand break repair

E3 泛素连接酶定位筛选发现 DTX2 是一种新型的 ADP 核糖基化依赖性 DNA 双链断裂修复调节剂

Billel Djerir, Isabelle Marois, Jean-Christophe Dubois, Steven Findlay, Théo Morin, Issam Senoussi, Laurent Cappadocia, Alexandre Orthwein, Alexandre Maréchal

The Deubiquitylase Otub1 Regulates the Chemotactic Response of Splenic B Cells by Modulating the Stability of the γ-Subunit Gng2

去泛素化酶 Otub1 通过调节 γ 亚基 Gng2 的稳定性来调控脾脏 B 细胞的趋化反应。

Vincent M Luo ,Connie Shen ,Samantha Worme ,Aanya Bhagrath ,Estelle Simo-Cheyou ,Steven Findlay ,Steven Hébert ,William Wai Lam Poon ,Zahra Aryanpour ,Thomas Zhang ,René P Zahedi ,Jonathan Boulais ,Zachary S Buchwald ,Christoph H Borchers ,Jean-Francois Côté ,Claudia L Kleinman ,Judith N Mandl ,Alexandre Orthwein

Radiation and anti-PD-L1 synergize by stimulating a stem-like T cell population in the tumor-draining lymph node

放射线和抗PD-L1疗法通过刺激肿瘤引流淋巴结中的干细胞样T细胞群发挥协同作用。

Shen, Yang; Connolly, Erin; Aiello, Meili; Zhou, Chengjing; Chappa, Prasanthi; Song, Haorui; Tippitak, Patan; Clark, Tarralyn; Cardenas, Maria; Prokhnevska, Nataliya; Mariniello, Annapaola; Pagadala, Meghana S; Dhere, Vishal R; Rafiq, Sarwish; Kesarwala, Aparna H; Orthwein, Alexandre; Thomas, Susan N; Khan, Mohammad K; Brandon Dixon, J; Lesinski, Gregory B; Lowe, Michael C; Kissick, Haydn; Yu, David S; Paulos, Chrystal M; Schmitt, Nicole C; Buchwald, Zachary S

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair

FIRRM与FIGNL1协同作用,促进DNA修复过程中RAD51的解离。

Edgar Pinedo-Carpio,Julien Dessapt,Adèle Beneyton,Lauralicia Sacre,Marie-Anne Bérubé,Romain Villot,Elise G Lavoie,Yan Coulombe,Andréanne Blondeau,Jonathan Boulais,Abba Malina,Vincent M Luo,Anna-Maria Lazaratos,Jean-François Côté,Frédérick A Mallette,Alba Guarné,Jean-Yves Masson,Amélie Fradet-Turcotte,Alexandre Orthwein

Interlaboratory Reproducibility in Growth and Reporter Expression in the Cyanobacterium Synechocystis sp. PCC 6803

蓝藻集胞藻 PCC 6803 生长和报告基因表达的实验室间重复性

Mager, Maurice; Pineda Hernandez, Hugo; Brandenburg, Fabian; López-Maury, Luis; McCormick, Alistair J; Nürnberg, Dennis J; Orthwein, Tim; Russo, David A; Victoria, Angelo Joshua; Wang, Xiaoran; Zedler, Julie A Z; Branco Dos Santos, Filipe; Schmelling, Nicolas M

B cell-specific knockout of AID protects against atherosclerosis

B细胞特异性敲除AID可预防动脉粥样硬化

Ebrahimian, Talin; Dierick, France; Ta, Vincent; Kotsiopriftis, Maria; O'Connor Miranda, Jonathan; Mann, Koren K; Orthwein, Alexandre; Lehoux, Stephanie