日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Novel druggable space in human KRAS G13D discovered using structural bioinformatics and a P-loop targeting monoclonal antibody

利用结构生物信息学和 P 环靶向单克隆抗体发现人类 KRAS G13D 中的新型可用药空间

Oscar Jungholm #, Carolina Trkulja #, Martin Moche #, Sreesha P Srinivasa, Maria-Nefeli Christakopoulou, Max Davidson, Anna Reymer, Kent Jardemark, Rafaela Lenza Fogaça, Anaswara Ashok, Gavin Jeffries, Henry Ampah-Korsah, Emilia Strandback, Juni Andréll, Tomas Nyman, Ghada Nouairia, Owe Orwar

3D micro-organisation printing of mammalian cells to generate biological tissues

3D微组织打印哺乳动物细胞以生成生物组织

Gavin D M Jeffries, Shijun Xu, Tatsiana Lobovkina, Vladimir Kirejev, Florian Tusseau, Christoffer Gyllensten, Avadhesh Kumar Singh, Paul Karila, Lydia Moll, Owe Orwar

Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy

胞质硫氧还蛋白还原酶1的不可逆抑制是抗癌治疗的机制基础

Stafford, William C; Peng, Xiaoxiao; Olofsson, Maria Hägg; Zhang, Xiaonan; Luci, Diane K; Lu, Li; Cheng, Qing; Trésaugues, Lionel; Dexheimer, Thomas S; Coussens, Nathan P; Augsten, Martin; Ahlzén, Hanna-Stina Martinsson; Orwar, Owe; Östman, Arne; Stone-Elander, Sharon; Maloney, David J; Jadhav, Ajit; Simeonov, Anton; Linder, Stig; Arnér, Elias S J

Spatial characterization of a multifunctional pipette for drug delivery in hippocampal brain slices

用于海马脑切片药物输送的多功能移液管的空间特性分析

Ahemaiti, Aikeremu; Wigström, Holger; Ainla, Alar; Jeffries, Gavin D M; Orwar, Owe; Jesorka, Aldo; Jardemark, Kent

Effect of cholesterol depletion on the pore dilation of TRPV1

胆固醇耗竭对TRPV1孔道扩张的影响

Jansson, Erik T; Trkulja, Carolina L; Ahemaiti, Aikeremu; Millingen, Maria; Jeffries, Gavin Dm; Jardemark, Kent; Orwar, Owe

Radial sizing of lipid nanotubes using membrane displacement analysis

利用膜置换分析法测定脂质纳米管的径向尺寸

Stepanyants, Natalia; Jeffries, Gavin D M; Orwar, Owe; Jesorka, Aldo

Control of the release of freely diffusing molecules in single-cell electroporation

单细胞电穿孔中自由扩散分子释放的控制

Agarwal, Aparna; Wang, Manyan; Olofsson, Jessica; Orwar, Owe; Weber, Stephen G

Controlling the rates of biochemical reactions and signaling networks by shape and volume changes

通过形状和体积变化来控制生化反应速率和信号网络。

Lizana, L; Bauer, B; Orwar, O

Effect of cell size and shape on single-cell electroporation

细胞大小和形状对单细胞电穿孔的影响

Agarwal, Aparna; Zudans, Imants; Weber, Emily A; Olofsson, Jessica; Orwar, Owe; Weber, Stephen G

Numerical calculations of single-cell electroporation with an electrolyte-filled capillary

利用充满电解质的毛细管进行单细胞电穿孔的数值计算

Zudans, Imants; Agarwal, Aparna; Orwar, Owe; Weber, Stephen G